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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

TRICHLORMETHIAZIDE: 342 Adverse Event Reports & Safety Profile

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342
Total FAERS Reports
24 (7.0%)
Deaths Reported
240
Hospitalizations
342
As Primary/Secondary Suspect
24
Life-Threatening
9
Disabilities
Approved Prior to Jan 1, 1982
FDA Approved
Discontinued
Status
Yes
Generic Available

FDA Application: 012265 ·

First Report: 20010803 · Latest Report: 20250226

What Are the Most Common TRICHLORMETHIAZIDE Side Effects?

#1 Most Reported
Dyspnoea
105 reports (30.7%)
#2 Most Reported
Cough
104 reports (30.4%)
#3 Most Reported
Obstructive airways disorder
103 reports (30.1%)

All TRICHLORMETHIAZIDE Side Effects by Frequency

Side Effect Reports % of Total Deaths Hosp.
Dyspnoea 105 30.7% 0 99
Cough 104 30.4% 0 97
Drug ineffective 103 30.1% 0 99
Obstructive airways disorder 103 30.1% 0 97
Pneumonia 101 29.5% 1 100
Bronchial secretion retention 97 28.4% 0 97
Eosinophil count increased 97 28.4% 0 97
Multiple allergies 97 28.4% 0 97
Pulmonary mass 97 28.4% 0 97
Sputum culture positive 97 28.4% 0 97
Upper-airway cough syndrome 97 28.4% 0 97
Respiratory tract infection 96 28.1% 0 96
Vital capacity decreased 96 28.1% 0 96
Reversible airways obstruction 95 27.8% 0 95
Full blood count abnormal 79 23.1% 0 75
Hyponatraemia 28 8.2% 3 21
Blood count abnormal 24 7.0% 0 22
Sputum culture 21 6.1% 0 21
Acute kidney injury 20 5.9% 1 16
Dehydration 20 5.9% 3 17

Who Reports TRICHLORMETHIAZIDE Side Effects? Age & Gender Data

Gender: 66.0% female, 34.0% male. Average age: 75.9 years. Most reports from: JP. View detailed demographics →

Is TRICHLORMETHIAZIDE Getting Safer? Reports by Year

YearReportsDeathsHosp.
2001 2 0 2
2009 1 1 0
2010 2 0 0
2011 2 1 2
2012 8 0 6
2013 9 1 8
2014 7 2 6
2015 8 1 2
2016 18 3 13
2017 25 5 18
2018 16 2 10
2019 10 1 8
2020 4 1 3
2021 5 0 4
2022 10 3 4
2023 3 1 2
2024 4 0 3
2025 1 0 1

View full timeline →

What Is TRICHLORMETHIAZIDE Used For?

IndicationReports
Product used for unknown indication 174
Hypertension 65
Cardiac failure 14
Blood pressure abnormal 9
Cardiac failure congestive 9
Cardiac failure chronic 5

TRICHLORMETHIAZIDE vs Alternatives: Which Is Safer?

TRICHLORMETHIAZIDE vs TRICLOSAN TRICHLORMETHIAZIDE vs TRIENTINE TRICHLORMETHIAZIDE vs TRIENTINE TETRAHYDROCHLORIDE TRICHLORMETHIAZIDE vs TRIFAROTENE TRICHLORMETHIAZIDE vs TRIFLUOPERAZINE TRICHLORMETHIAZIDE vs TRIFLURIDINE TRICHLORMETHIAZIDE vs TRIHEPTANOIN TRICHLORMETHIAZIDE vs TRIHEXYPHENIDYL TRICHLORMETHIAZIDE vs TRILACICLIB TRICHLORMETHIAZIDE vs TRILEPTAL

Official FDA Label for TRICHLORMETHIAZIDE

Official prescribing information from the FDA-approved drug label.