TROFOSFAMIDE for Alveolar rhabdomyosarcoma: Side Effects & Safety Data
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There are 12 adverse event reports in the FDA FAERS database where TROFOSFAMIDE was used for Alveolar rhabdomyosarcoma.
Most Reported Side Effects for TROFOSFAMIDE
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Acute myeloid leukaemia | 18 | 16.5% | 9 | 1 |
| Myelodysplastic syndrome | 18 | 16.5% | 9 | 1 |
| Product use in unapproved indication | 16 | 14.7% | 0 | 2 |
| Off label use | 15 | 13.8% | 2 | 1 |
| Neutropenia | 14 | 12.8% | 1 | 6 |
| Anaemia | 13 | 11.9% | 0 | 0 |
| Dyspnoea | 12 | 11.0% | 0 | 7 |
| Oedema | 10 | 9.2% | 0 | 0 |
| Pleural effusion | 10 | 9.2% | 0 | 5 |
| Hepatosplenomegaly | 9 | 8.3% | 0 | 0 |
| Hyperleukocytosis | 9 | 8.3% | 1 | 0 |
| Rhabdomyosarcoma recurrent | 9 | 8.3% | 2 | 0 |
| Thrombocytopenia | 9 | 8.3% | 0 | 0 |
| Neoplasm progression | 8 | 7.3% | 2 | 0 |
| Acute kidney injury | 7 | 6.4% | 1 | 5 |
Other Indications for TROFOSFAMIDE
Metastatic malignant melanoma (32)
Diffuse large b-cell lymphoma (13)
Langerhans' cell histiocytosis (11)
Angioimmunoblastic t-cell lymphoma (6)
Product used for unknown indication (6)
Hodgkin's disease (5)
Lymphoma (5)
Other Drugs Used for Alveolar rhabdomyosarcoma
VINCRISTINE (181)
DACTINOMYCIN (134)
CYCLOPHOSPHAMIDE (126)
IRINOTECAN (114)
IFOSFAMIDE (110)
DOXORUBICIN (71)
ETOPOSIDE (58)
CARBOPLATIN (39)
TEMSIROLIMUS (38)
VINORELBINE (23)