TROPATEPINE: 1,458 Adverse Event Reports & Safety Profile
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1,458
Total FAERS Reports
290 (19.9%)
Deaths Reported
831
Hospitalizations
1,458
As Primary/Secondary Suspect
225
Life-Threatening
25
Disabilities
Active Ingredient: TROPATEPINE HYDROCHLORIDE ·
First Report: 20050226 · Latest Report: 20250822
What Are the Most Common TROPATEPINE Side Effects?
#1 Most Reported
Coma
132 reports (9.1%)
#2 Most Reported
Somnolence
112 reports (7.7%)
#3 Most Reported
Intestinal obstruction
85 reports (5.8%)
All TROPATEPINE Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Coma | 132 | 9.1% | 9 | 107 |
| Somnolence | 112 | 7.7% | 8 | 80 |
| Confusional state | 85 | 5.8% | 2 | 65 |
| Intestinal obstruction | 85 | 5.8% | 31 | 39 |
| Death | 84 | 5.8% | 84 | 7 |
| Acute kidney injury | 69 | 4.7% | 17 | 54 |
| Poisoning deliberate | 68 | 4.7% | 0 | 60 |
| Hypotension | 61 | 4.2% | 4 | 36 |
| Septic shock | 61 | 4.2% | 17 | 32 |
| Drug abuse | 54 | 3.7% | 26 | 30 |
| Fall | 53 | 3.6% | 5 | 31 |
| Pneumonia aspiration | 53 | 3.6% | 11 | 35 |
| Constipation | 52 | 3.6% | 3 | 40 |
| Toxicity to various agents | 52 | 3.6% | 12 | 45 |
| Off label use | 48 | 3.3% | 5 | 32 |
| Wrong patient received product | 44 | 3.0% | 5 | 23 |
| Colitis ischaemic | 43 | 3.0% | 7 | 26 |
| Cardio-respiratory arrest | 41 | 2.8% | 40 | 1 |
| Product use in unapproved indication | 39 | 2.7% | 3 | 25 |
| Rhabdomyolysis | 38 | 2.6% | 6 | 31 |
Who Reports TROPATEPINE Side Effects? Age & Gender Data
Gender: 42.1% female, 57.9% male. Average age: 43.4 years. Most reports from: FR. View detailed demographics →
Is TROPATEPINE Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2005 | 3 | 1 | 1 |
| 2007 | 7 | 0 | 4 |
| 2008 | 12 | 11 | 7 |
| 2009 | 2 | 0 | 2 |
| 2010 | 5 | 0 | 4 |
| 2011 | 3 | 1 | 2 |
| 2012 | 52 | 18 | 42 |
| 2013 | 10 | 0 | 10 |
| 2014 | 60 | 8 | 53 |
| 2015 | 50 | 5 | 38 |
| 2016 | 87 | 13 | 61 |
| 2017 | 99 | 14 | 58 |
| 2018 | 113 | 16 | 58 |
| 2019 | 142 | 35 | 75 |
| 2020 | 146 | 6 | 95 |
| 2021 | 145 | 10 | 86 |
| 2022 | 92 | 23 | 52 |
| 2023 | 99 | 30 | 50 |
| 2024 | 146 | 24 | 77 |
| 2025 | 40 | 4 | 22 |
What Is TROPATEPINE Used For?
| Indication | Reports |
|---|---|
| Product used for unknown indication | 512 |
| Parkinsonism | 233 |
| Extrapyramidal disorder | 74 |
| Schizophrenia | 72 |
| Psychotic disorder | 61 |
| Bipolar disorder | 52 |
| Dyskinesia | 40 |
| Prophylaxis | 36 |
| Intentional overdose | 32 |
| Mental disorder | 27 |
TROPATEPINE vs Alternatives: Which Is Safer?
TROPATEPINE vs TROPICAMIDE
TROPATEPINE vs TROSPIUM
TROPATEPINE vs TROSPIUM\XANOMELINE
TROPATEPINE vs TRUVADA
TROPATEPINE vs TRYPTOPHAN
TROPATEPINE vs TUBERCULIN PURIFIED PROTEIN DERIVATIVE
TROPATEPINE vs TUCATINIB
TROPATEPINE vs TUCIDINOSTAT
TROPATEPINE vs TYKERB
TROPATEPINE vs TYLENOL
Official FDA Label for TROPATEPINE
Official prescribing information from the FDA-approved drug label.