TYKERB: 533 Adverse Event Reports & Safety Profile
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533
Total FAERS Reports
73 (13.7%)
Deaths Reported
68
Hospitalizations
533
As Primary/Secondary Suspect
7
Life-Threatening
9
Disabilities
First Report: 20070505 · Latest Report: 20140606
What Are the Most Common TYKERB Side Effects?
#1 Most Reported
Diarrhoea
173 reports (32.5%)
#2 Most Reported
Nausea
63 reports (11.8%)
#3 Most Reported
Death
47 reports (8.8%)
All TYKERB Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Diarrhoea | 173 | 32.5% | 3 | 12 |
| Nausea | 63 | 11.8% | 7 | 10 |
| Death | 47 | 8.8% | 47 | 1 |
| Fatigue | 44 | 8.3% | 3 | 5 |
| Drug ineffective | 42 | 7.9% | 1 | 4 |
| Rash | 37 | 6.9% | 0 | 2 |
| Disease progression | 29 | 5.4% | 10 | 3 |
| Vomiting | 29 | 5.4% | 2 | 7 |
| Decreased appetite | 28 | 5.3% | 3 | 2 |
| Palmar-plantar erythrodysaesthesia syndrome | 23 | 4.3% | 0 | 3 |
| Weight decreased | 23 | 4.3% | 2 | 4 |
| Dizziness | 22 | 4.1% | 4 | 8 |
| Dry skin | 22 | 4.1% | 0 | 1 |
| Stomatitis | 19 | 3.6% | 1 | 2 |
| Malaise | 18 | 3.4% | 0 | 0 |
| Malignant neoplasm progression | 18 | 3.4% | 2 | 7 |
| Skin fissures | 17 | 3.2% | 0 | 3 |
| Asthenia | 15 | 2.8% | 2 | 4 |
| Cough | 15 | 2.8% | 2 | 6 |
| Neuropathy peripheral | 15 | 2.8% | 0 | 0 |
Who Reports TYKERB Side Effects? Age & Gender Data
Average age: 57.3 years. Most reports from: US. View detailed demographics →
Is TYKERB Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2007 | 1 | 0 | 0 |
| 2008 | 1 | 0 | 0 |
| 2009 | 4 | 0 | 0 |
| 2010 | 7 | 1 | 1 |
| 2011 | 10 | 0 | 3 |
| 2012 | 17 | 0 | 1 |
| 2013 | 114 | 7 | 15 |
| 2014 | 46 | 18 | 16 |
What Is TYKERB Used For?
| Indication | Reports |
|---|---|
| Breast cancer | 282 |
| Product used for unknown indication | 133 |
| Breast cancer metastatic | 54 |
| Breast cancer female | 12 |
| Neoplasm malignant | 10 |
TYKERB vs Alternatives: Which Is Safer?
TYKERB vs TYLENOL
TYKERB vs TYROTHRICIN
TYKERB vs TYSABRI
TYKERB vs TYVASO
TYKERB vs UBIDECARENONE
TYKERB vs UBLITUXIMAB
TYKERB vs UBLITUXIMAB-XIIY
TYKERB vs UBROGEPANT
TYKERB vs ULIPRISTAL
TYKERB vs UMBRALISIB
Official FDA Label for TYKERB
Official prescribing information from the FDA-approved drug label.