UMBRALISIB: 293 Adverse Event Reports & Safety Profile
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293
Total FAERS Reports
30 (10.2%)
Deaths Reported
97
Hospitalizations
293
As Primary/Secondary Suspect
10
Life-Threatening
8
Disabilities
Feb 5, 2021
FDA Approved
Discontinued
Status
FDA Application: 213176 ·
Patent Expires: May 26, 2035 · First Report: 20120101 · Latest Report: 20230720
What Are the Most Common UMBRALISIB Side Effects?
#1 Most Reported
Diarrhoea
47 reports (16.0%)
#2 Most Reported
Nausea
36 reports (12.3%)
#3 Most Reported
Fatigue
30 reports (10.2%)
All UMBRALISIB Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Diarrhoea | 47 | 16.0% | 2 | 5 |
| Nausea | 36 | 12.3% | 1 | 5 |
| Disease progression | 30 | 10.2% | 2 | 3 |
| Fatigue | 30 | 10.2% | 1 | 0 |
| Covid-19 | 16 | 5.5% | 3 | 13 |
| Nervous system disorder | 15 | 5.1% | 0 | 0 |
| Death | 14 | 4.8% | 14 | 4 |
| Asthenia | 13 | 4.4% | 1 | 2 |
| Off label use | 13 | 4.4% | 1 | 0 |
| Product dose omission issue | 12 | 4.1% | 0 | 3 |
| Anaemia | 11 | 3.8% | 0 | 0 |
| Decreased appetite | 11 | 3.8% | 1 | 2 |
| Pyrexia | 11 | 3.8% | 0 | 0 |
| Dizziness | 10 | 3.4% | 0 | 3 |
| Drug ineffective | 10 | 3.4% | 0 | 0 |
| Dyspnoea | 10 | 3.4% | 1 | 6 |
| Headache | 10 | 3.4% | 0 | 1 |
| Pneumonia | 10 | 3.4% | 1 | 7 |
| Vomiting | 10 | 3.4% | 1 | 3 |
| Abdominal pain | 9 | 3.1% | 0 | 2 |
Who Reports UMBRALISIB Side Effects? Age & Gender Data
Gender: 43.8% female, 56.2% male. Average age: 69.0 years. Most reports from: US. View detailed demographics →
Is UMBRALISIB Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2012 | 1 | 0 | 0 |
| 2016 | 1 | 0 | 1 |
| 2017 | 7 | 0 | 2 |
| 2018 | 2 | 0 | 2 |
| 2019 | 5 | 0 | 2 |
| 2020 | 19 | 3 | 13 |
| 2021 | 107 | 16 | 46 |
| 2022 | 42 | 5 | 19 |
| 2023 | 1 | 0 | 1 |
What Is UMBRALISIB Used For?
| Indication | Reports |
|---|---|
| Chronic lymphocytic leukaemia | 66 |
| Non-hodgkin's lymphoma | 50 |
| Follicular lymphoma | 48 |
| Product used for unknown indication | 42 |
| Diffuse large b-cell lymphoma | 20 |
| Marginal zone lymphoma | 20 |
| B-cell lymphoma | 18 |
| Lymphoma | 9 |
UMBRALISIB vs Alternatives: Which Is Safer?
UMBRALISIB vs UMECLIDINIUM
UMBRALISIB vs UMECLIDINIUM\VILANTEROL TRIFENATATE
UMBRALISIB vs UMIFENOVIR
UMBRALISIB vs UNSPECIFIED INGREDIENT
UMBRALISIB vs UPADACITINIB
UMBRALISIB vs URAPIDIL
UMBRALISIB vs UREA
UMBRALISIB vs URIDINE TRIACETATE
UMBRALISIB vs UROFOLLITROPIN
UMBRALISIB vs URSODIOL
Official FDA Label for UMBRALISIB
Official prescribing information from the FDA-approved drug label.