Does VALPROATE Cause Leukopenia? 192 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 192 reports of Leukopenia have been filed in association with VALPROATE (Valproate Sodium). This represents 1.2% of all adverse event reports for VALPROATE.
192
Reports of Leukopenia with VALPROATE
1.2%
of all VALPROATE reports
4
Deaths
106
Hospitalizations
How Dangerous Is Leukopenia From VALPROATE?
Of the 192 reports, 4 (2.1%) resulted in death, 106 (55.2%) required hospitalization, and 17 (8.9%) were considered life-threatening.
Is Leukopenia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VALPROATE. However, 192 reports have been filed with the FAERS database.
What Other Side Effects Does VALPROATE Cause?
Foetal exposure during pregnancy (1,982)
Drug ineffective (1,268)
Seizure (1,083)
Epilepsy (878)
Somnolence (843)
Off label use (744)
Drug abuse (705)
Sopor (577)
Dysmorphism (552)
Drug interaction (513)
What Other Drugs Cause Leukopenia?
METHOTREXATE (2,694)
CYCLOPHOSPHAMIDE (2,482)
RITUXIMAB (2,191)
CLOZAPINE (2,036)
PREDNISONE (1,725)
DOXORUBICIN (1,696)
PACLITAXEL (1,649)
CARBOPLATIN (1,624)
DEXAMETHASONE (1,542)
MYCOPHENOLATE MOFETIL (1,491)
Which VALPROATE Alternatives Have Lower Leukopenia Risk?
VALPROATE vs VALPROIC ACID
VALPROATE vs VALPROMIDE
VALPROATE vs VALSARTAN
VALPROATE vs VALTREX
VALPROATE vs VAMOROLONE