Does VALPROATE Cause Polydactyly? 25 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 25 reports of Polydactyly have been filed in association with VALPROATE (Valproate Sodium). This represents 0.2% of all adverse event reports for VALPROATE.
25
Reports of Polydactyly with VALPROATE
0.2%
of all VALPROATE reports
0
Deaths
5
Hospitalizations
How Dangerous Is Polydactyly From VALPROATE?
Of the 25 reports, 5 (20.0%) required hospitalization.
Is Polydactyly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VALPROATE. However, 25 reports have been filed with the FAERS database.
What Other Side Effects Does VALPROATE Cause?
Foetal exposure during pregnancy (1,982)
Drug ineffective (1,268)
Seizure (1,083)
Epilepsy (878)
Somnolence (843)
Off label use (744)
Drug abuse (705)
Sopor (577)
Dysmorphism (552)
Drug interaction (513)
What Other Drugs Cause Polydactyly?
LEVETIRACETAM (91)
EMTRICITABINE\TENOFOVIR DISOPROXIL (75)
LAMIVUDINE (68)
RITONAVIR (64)
NEVIRAPINE (57)
ABACAVIR (54)
LAMOTRIGINE (45)
LACOSAMIDE (42)
ABACAVIR\LAMIVUDINE (39)
ASPIRIN (36)
Which VALPROATE Alternatives Have Lower Polydactyly Risk?
VALPROATE vs VALPROIC ACID
VALPROATE vs VALPROMIDE
VALPROATE vs VALSARTAN
VALPROATE vs VALTREX
VALPROATE vs VAMOROLONE