VEDOLIZUMAB for Colitis: Side Effects & Safety Data
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There are 805 adverse event reports in the FDA FAERS database where VEDOLIZUMAB was used for Colitis.
Most Reported Side Effects for VEDOLIZUMAB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Off label use | 21,017 | 28.5% | 637 | 5,998 |
| Colitis ulcerative | 13,455 | 18.2% | 155 | 3,107 |
| Crohn's disease | 9,759 | 13.2% | 227 | 3,122 |
| Drug ineffective | 8,424 | 11.4% | 180 | 2,439 |
| Diarrhoea | 7,493 | 10.2% | 399 | 2,536 |
| Abdominal pain | 6,401 | 8.7% | 117 | 2,324 |
| Fatigue | 5,477 | 7.4% | 394 | 1,730 |
| Haematochezia | 5,215 | 7.1% | 8 | 1,046 |
| Frequent bowel movements | 4,527 | 6.1% | 103 | 1,188 |
| Arthralgia | 4,028 | 5.5% | 308 | 1,164 |
| Malaise | 3,684 | 5.0% | 262 | 1,565 |
| Nausea | 3,582 | 4.9% | 304 | 1,456 |
| Headache | 3,574 | 4.8% | 355 | 1,237 |
| Inappropriate schedule of product administration | 3,259 | 4.4% | 70 | 828 |
| Product dose omission issue | 3,078 | 4.2% | 47 | 859 |
Other Indications for VEDOLIZUMAB
Colitis ulcerative (33,987)
Crohn's disease (28,718)
Product used for unknown indication (8,955)
Inflammatory bowel disease (1,342)
Colitis microscopic (286)
Proctitis ulcerative (146)
Deep vein thrombosis (139)
Immune-mediated enterocolitis (89)
Pouchitis (86)
Graft versus host disease (71)
Other Drugs Used for Colitis
INFLIXIMAB (1,248)
MESALAMINE (804)
ADALIMUMAB (697)
TOFACITINIB (232)
USTEKINUMAB (219)
METRONIDAZOLE (214)
PREDNISONE (198)
PREDNISOLONE (188)
AZATHIOPRINE (181)
METHYLPREDNISOLONE (176)