Does VEMURAFENIB Cause Melaena? 7 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 7 reports of Melaena have been filed in association with VEMURAFENIB (ZELBORAF). This represents 0.1% of all adverse event reports for VEMURAFENIB.
7
Reports of Melaena with VEMURAFENIB
0.1%
of all VEMURAFENIB reports
2
Deaths
6
Hospitalizations
How Dangerous Is Melaena From VEMURAFENIB?
Of the 7 reports, 2 (28.6%) resulted in death, 6 (85.7%) required hospitalization, and 3 (42.9%) were considered life-threatening.
Is Melaena Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VEMURAFENIB. However, 7 reports have been filed with the FAERS database.
What Other Side Effects Does VEMURAFENIB Cause?
Rash (1,202)
Arthralgia (783)
Off label use (782)
Fatigue (773)
Diarrhoea (655)
Nausea (601)
Pyrexia (569)
Death (505)
Alopecia (445)
Decreased appetite (383)
What Other Drugs Cause Melaena?
ASPIRIN (2,001)
CLOPIDOGREL BISULFATE (1,547)
RIVAROXABAN (1,405)
APIXABAN (1,156)
WARFARIN (930)
IBUPROFEN (810)
DABIGATRAN ETEXILATE (700)
DICLOFENAC (576)
NAPROXEN (291)
FUROSEMIDE (272)
Which VEMURAFENIB Alternatives Have Lower Melaena Risk?
VEMURAFENIB vs VENETOCLAX
VEMURAFENIB vs VENLAFAXINE
VEMURAFENIB vs VENTAVIS
VEMURAFENIB vs VENTOLIN
VEMURAFENIB vs VENTOLIN HFA