VENETOCLAX for B-cell lymphoma refractory: Side Effects & Safety Data
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There are 26 adverse event reports in the FDA FAERS database where VENETOCLAX was used for B-cell lymphoma refractory.
Most Reported Side Effects for VENETOCLAX
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Death | 9,412 | 17.5% | 9,399 | 774 |
| Off label use | 6,252 | 11.6% | 2,257 | 1,642 |
| Neutropenia | 3,041 | 5.7% | 626 | 1,121 |
| Febrile neutropenia | 2,663 | 5.0% | 665 | 1,725 |
| Platelet count decreased | 2,367 | 4.4% | 311 | 1,357 |
| Pyrexia | 2,351 | 4.4% | 487 | 1,834 |
| Pneumonia | 2,300 | 4.3% | 790 | 1,683 |
| Fatigue | 2,281 | 4.3% | 168 | 920 |
| Diarrhoea | 2,082 | 3.9% | 278 | 964 |
| White blood cell count decreased | 1,913 | 3.6% | 198 | 1,007 |
| Myelosuppression | 1,864 | 3.5% | 84 | 756 |
| Thrombocytopenia | 1,834 | 3.4% | 404 | 653 |
| Nausea | 1,814 | 3.4% | 197 | 772 |
| Infection | 1,757 | 3.3% | 460 | 912 |
| Anaemia | 1,671 | 3.1% | 329 | 712 |
Other Indications for VENETOCLAX
Acute myeloid leukaemia (19,774)
Chronic lymphocytic leukaemia (14,194)
Product used for unknown indication (4,628)
Myelodysplastic syndrome (2,508)
Plasma cell myeloma (1,778)
Mantle cell lymphoma (1,367)
Diffuse large b-cell lymphoma (761)
Acute myeloid leukaemia recurrent (558)
B-cell small lymphocytic lymphoma (499)
Non-hodgkin's lymphoma (485)
Other Drugs Used for B-cell lymphoma refractory
RITUXIMAB (103)
OBINUTUZUMAB (84)
CISPLATIN (53)
ETOPOSIDE (49)
DEXAMETHASONE (45)
AXICABTAGENE CILOLEUCEL (44)
CYCLOPHOSPHAMIDE (43)
CYTARABINE (40)
IBRUTINIB (39)
LENALIDOMIDE (36)