VISMODEGIB for Medulloblastoma: Side Effects & Safety Data
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There are 52 adverse event reports in the FDA FAERS database where VISMODEGIB was used for Medulloblastoma.
Most Reported Side Effects for VISMODEGIB
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Muscle spasms | 1,937 | 23.8% | 24 | 110 |
| Alopecia | 1,330 | 16.4% | 28 | 81 |
| Ageusia | 958 | 11.8% | 7 | 49 |
| Fatigue | 899 | 11.1% | 20 | 78 |
| Dysgeusia | 706 | 8.7% | 18 | 40 |
| Weight decreased | 688 | 8.5% | 19 | 59 |
| Nausea | 669 | 8.2% | 8 | 72 |
| Decreased appetite | 662 | 8.1% | 21 | 69 |
| Death | 657 | 8.1% | 641 | 23 |
| Diarrhoea | 446 | 5.5% | 16 | 48 |
| Constipation | 361 | 4.4% | 3 | 31 |
| Off label use | 335 | 4.1% | 24 | 24 |
| Asthenia | 274 | 3.4% | 14 | 52 |
| Arthralgia | 264 | 3.3% | 0 | 20 |
| No adverse event | 247 | 3.0% | 1 | 0 |
Other Indications for VISMODEGIB
Basal cell carcinoma (5,329)
Product used for unknown indication (1,417)
Skin cancer (452)
Basal cell naevus syndrome (129)
Neoplasm malignant (124)
Congenital anomaly (54)
Squamous cell carcinoma of skin (42)
Malignant melanoma (38)
Neoplasm (36)
Neoplasm skin (36)
Other Drugs Used for Medulloblastoma
VINCRISTINE (587)
CYCLOPHOSPHAMIDE (543)
ETOPOSIDE (536)
CISPLATIN (438)
CARBOPLATIN (407)
METHOTREXATE (264)
THIOTEPA (184)
BEVACIZUMAB (178)
TEMOZOLOMIDE (163)
LOMUSTINE (123)