VORINOSTAT for Ewing's sarcoma: Side Effects & Safety Data
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There are 26 adverse event reports in the FDA FAERS database where VORINOSTAT was used for Ewing's sarcoma.
Most Reported Side Effects for VORINOSTAT
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Febrile neutropenia | 177 | 14.2% | 25 | 84 |
| Product use in unapproved indication | 122 | 9.8% | 16 | 4 |
| Thrombocytopenia | 89 | 7.1% | 16 | 13 |
| Off label use | 88 | 7.1% | 18 | 28 |
| Anaemia | 79 | 6.3% | 15 | 28 |
| Sepsis | 77 | 6.2% | 28 | 40 |
| Diarrhoea | 68 | 5.5% | 10 | 30 |
| Neutropenia | 63 | 5.1% | 5 | 12 |
| Nausea | 61 | 4.9% | 14 | 29 |
| Fatigue | 59 | 4.7% | 13 | 19 |
| Product use issue | 55 | 4.4% | 6 | 3 |
| Platelet count decreased | 51 | 4.1% | 16 | 35 |
| Vomiting | 50 | 4.0% | 10 | 28 |
| Pneumonia | 47 | 3.8% | 19 | 27 |
| Death | 46 | 3.7% | 46 | 12 |
Other Indications for VORINOSTAT
Acute myeloid leukaemia (253)
Plasma cell myeloma (93)
Mycosis fungoides (82)
Myelodysplastic syndrome (81)
Acute lymphocytic leukaemia (69)
Product used for unknown indication (52)
Cutaneous t-cell lymphoma (38)
Peripheral t-cell lymphoma unspecified (34)
Neoplasm malignant (21)
Neuroblastoma (21)
Other Drugs Used for Ewing's sarcoma
DOXORUBICIN (1,047)
VINCRISTINE (993)
ETOPOSIDE (978)
IFOSFAMIDE (937)
CYCLOPHOSPHAMIDE (721)
DACTINOMYCIN (282)
IRINOTECAN (155)
TEMOZOLOMIDE (148)
MESNA (88)
CABOZANTINIB S-MALATE (84)