Does VOXELOTOR Cause Haemolysis? 17 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 17 reports of Haemolysis have been filed in association with VOXELOTOR (OXBRYTA). This represents 0.1% of all adverse event reports for VOXELOTOR.
17
Reports of Haemolysis with VOXELOTOR
0.1%
of all VOXELOTOR reports
1
Deaths
11
Hospitalizations
How Dangerous Is Haemolysis From VOXELOTOR?
Of the 17 reports, 1 (5.9%) resulted in death, 11 (64.7%) required hospitalization, and 1 (5.9%) were considered life-threatening.
Is Haemolysis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for VOXELOTOR. However, 17 reports have been filed with the FAERS database.
What Other Side Effects Does VOXELOTOR Cause?
Sickle cell anaemia with crisis (11,023)
Product dose omission issue (5,122)
Diarrhoea (3,173)
Off label use (2,364)
Nausea (2,003)
Headache (1,683)
Abdominal pain upper (1,165)
Pain (1,059)
Therapy cessation (1,038)
Fatigue (1,004)
What Other Drugs Cause Haemolysis?
ECULIZUMAB (1,476)
HUMAN IMMUNOGLOBULIN G (357)
RITUXIMAB (261)
RAVULIZUMAB-CWVZ (242)
PREDNISONE (192)
CYCLOSPORINE (173)
DEXAMETHASONE (167)
ACETAMINOPHEN (134)
VINCRISTINE (132)
TACROLIMUS (116)
Which VOXELOTOR Alternatives Have Lower Haemolysis Risk?
VOXELOTOR vs VUTRISIRAN
VOXELOTOR vs VX-770
VOXELOTOR vs VX-950
VOXELOTOR vs VYVANSE
VOXELOTOR vs WARFARIN