VUTRISIRAN for Amyloidosis: Side Effects & Safety Data
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There are 22 adverse event reports in the FDA FAERS database where VUTRISIRAN was used for Amyloidosis.
Most Reported Side Effects for VUTRISIRAN
| Side Effect | Reports | % | Deaths | Hosp. |
|---|---|---|---|---|
| Death | 244 | 17.1% | 244 | 18 |
| Hospitalisation | 143 | 10.0% | 6 | 143 |
| Intentional dose omission | 80 | 5.6% | 5 | 68 |
| Therapy interrupted | 66 | 4.6% | 2 | 46 |
| Fall | 65 | 4.6% | 7 | 38 |
| Fatigue | 56 | 3.9% | 0 | 14 |
| Product dose omission issue | 45 | 3.2% | 11 | 25 |
| Pain in extremity | 43 | 3.0% | 0 | 9 |
| Dyspnoea | 42 | 3.0% | 2 | 20 |
| Gait disturbance | 42 | 3.0% | 1 | 15 |
| Asthenia | 37 | 2.6% | 1 | 22 |
| Arthralgia | 36 | 2.5% | 0 | 12 |
| Cardiac failure | 35 | 2.5% | 12 | 18 |
| Dizziness | 34 | 2.4% | 0 | 13 |
| Neuropathy peripheral | 34 | 2.4% | 0 | 2 |
Other Indications for VUTRISIRAN
Hereditary neuropathic amyloidosis (965)
Product used for unknown indication (324)
Acquired attr amyloidosis (60)
Cardiac amyloidosis (34)
Familial amyloidosis (6)
Other Drugs Used for Amyloidosis
TAFAMIDIS (2,264)
LENALIDOMIDE (1,315)
BORTEZOMIB (1,044)
DEXAMETHASONE (932)
TAFAMIDIS MEGLUMINE (641)
CYCLOPHOSPHAMIDE (585)
POMALIDOMIDE (477)
DARATUMUMAB (417)
IXAZOMIB (168)
MELPHALAN (145)