Does ZOLEDRONIC ACID Cause Osteosclerosis? 124 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 124 reports of Osteosclerosis have been filed in association with ZOLEDRONIC ACID (Zoledronic acid). This represents 0.4% of all adverse event reports for ZOLEDRONIC ACID.
124
Reports of Osteosclerosis with ZOLEDRONIC ACID
0.4%
of all ZOLEDRONIC ACID reports
25
Deaths
35
Hospitalizations
How Dangerous Is Osteosclerosis From ZOLEDRONIC ACID?
Of the 124 reports, 25 (20.2%) resulted in death, 35 (28.2%) required hospitalization, and 1 (0.8%) were considered life-threatening.
Is Osteosclerosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for ZOLEDRONIC ACID. However, 124 reports have been filed with the FAERS database.
What Other Side Effects Does ZOLEDRONIC ACID Cause?
Osteonecrosis of jaw (5,500)
Death (3,053)
Pain (2,925)
Arthralgia (2,541)
Pyrexia (2,455)
Fatigue (2,219)
Nausea (1,962)
Malaise (1,834)
Headache (1,739)
Asthenia (1,582)
What Other Drugs Cause Osteosclerosis?
METHOTREXATE (166)
ETANERCEPT (131)
ZOMETA (123)
ABATACEPT (115)
LEFLUNOMIDE (115)
ADALIMUMAB (106)
AREDIA (82)
RITUXIMAB (78)
DENOSUMAB (76)
SULFASALAZINE (64)
Which ZOLEDRONIC ACID Alternatives Have Lower Osteosclerosis Risk?
ZOLEDRONIC ACID vs ZOLMITRIPTAN
ZOLEDRONIC ACID vs ZOLOFT
ZOLEDRONIC ACID vs ZOLPIDEM
ZOLEDRONIC ACID vs ZOLPIDEM\ZOLPIDEM
ZOLEDRONIC ACID vs ZOMETA