ZOMETA: 870 Adverse Event Reports & Safety Profile
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870
Total FAERS Reports
255 (29.3%)
Deaths Reported
350
Hospitalizations
870
As Primary/Secondary Suspect
19
Life-Threatening
42
Disabilities
First Report: 1995 · Latest Report: 20140610
What Are the Most Common ZOMETA Side Effects?
#1 Most Reported
Osteonecrosis of jaw
386 reports (44.4%)
#2 Most Reported
Pain
234 reports (26.9%)
#3 Most Reported
Anxiety
195 reports (22.4%)
All ZOMETA Side Effects by Frequency
| Side Effect | Reports | % of Total | Deaths | Hosp. |
|---|---|---|---|---|
| Osteonecrosis of jaw | 386 | 44.4% | 78 | 177 |
| Pain | 234 | 26.9% | 68 | 149 |
| Anxiety | 195 | 22.4% | 60 | 123 |
| Dyspnoea | 169 | 19.4% | 57 | 119 |
| Spinal osteoarthritis | 166 | 19.1% | 48 | 115 |
| Osteoarthritis | 160 | 18.4% | 50 | 113 |
| Arthralgia | 156 | 17.9% | 45 | 105 |
| Exposed bone in jaw | 153 | 17.6% | 38 | 88 |
| Osteomyelitis | 152 | 17.5% | 40 | 96 |
| Death | 147 | 16.9% | 147 | 38 |
| Anaemia | 143 | 16.4% | 46 | 96 |
| Back pain | 143 | 16.4% | 49 | 97 |
| Pain in jaw | 141 | 16.2% | 48 | 86 |
| Fatigue | 140 | 16.1% | 42 | 82 |
| Injury | 138 | 15.9% | 33 | 81 |
| Fall | 136 | 15.6% | 49 | 99 |
| Metastases to bone | 131 | 15.1% | 55 | 78 |
| Atelectasis | 129 | 14.8% | 47 | 97 |
| Neuropathy peripheral | 129 | 14.8% | 37 | 88 |
| Chest pain | 126 | 14.5% | 37 | 87 |
Who Reports ZOMETA Side Effects? Age & Gender Data
Average age: 65.8 years. Most reports from: COUNTRY NOT SPECIFIED. View detailed demographics →
Is ZOMETA Getting Safer? Reports by Year
| Year | Reports | Deaths | Hosp. |
|---|---|---|---|
| 2000 | 3 | 2 | 3 |
| 2001 | 6 | 4 | 5 |
| 2002 | 15 | 3 | 12 |
| 2003 | 24 | 10 | 14 |
| 2004 | 22 | 9 | 19 |
| 2005 | 17 | 6 | 15 |
| 2006 | 11 | 3 | 6 |
| 2007 | 27 | 7 | 13 |
| 2008 | 15 | 3 | 7 |
| 2009 | 28 | 6 | 15 |
| 2010 | 29 | 10 | 17 |
| 2011 | 20 | 3 | 13 |
| 2012 | 60 | 7 | 27 |
| 2013 | 178 | 44 | 67 |
| 2014 | 143 | 50 | 50 |
What Is ZOMETA Used For?
| Indication | Reports |
|---|---|
| Metastases to bone | 195 |
| Plasma cell myeloma | 123 |
| Breast cancer metastatic | 81 |
| Prostate cancer metastatic | 80 |
| Breast cancer | 59 |
| Osteoporosis | 31 |
| Prostate cancer | 29 |
| Product used for unknown indication | 20 |
| Bone cancer | 18 |
| Neoplasm malignant | 17 |
ZOMETA vs Alternatives: Which Is Safer?
ZOMETA vs ZONISAMIDE
ZOMETA vs ZOPICLONE
ZOMETA vs ZOTEPINE
ZOMETA vs ZUCLOPENTHIXOL
ZOMETA vs ZUCLOPENTHIXOL DECANOATE
ZOMETA vs ZURANOLONE
ZOMETA vs ZYPREXA
ZOMETA vs ZYTIGA
ZOMETA vs ZYVOX
ZOMETA vs 5-FLUOROURACIL
Official FDA Label for ZOMETA
Official prescribing information from the FDA-approved drug label.