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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

ZUCLOPENTHIXOL: 2,408 Adverse Event Reports & Safety Profile

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2,408
Total FAERS Reports
355 (14.7%)
Deaths Reported
1,122
Hospitalizations
2,408
As Primary/Secondary Suspect
196
Life-Threatening
51
Disabilities

First Report: 1986 · Latest Report: 20250822

What Are the Most Common ZUCLOPENTHIXOL Side Effects?

#1 Most Reported
Drug ineffective
660 reports (27.4%)
#2 Most Reported
Dyskinesia
414 reports (17.2%)
#3 Most Reported
Schizophrenia
409 reports (17.0%)

All ZUCLOPENTHIXOL Side Effects by Frequency

Side Effect Reports % of Total Deaths Hosp.
Drug ineffective 660 27.4% 47 179
Dyskinesia 414 17.2% 41 23
Schizophrenia 409 17.0% 111 117
Dystonia 404 16.8% 41 18
Sedation 403 16.7% 45 24
Sexual dysfunction 394 16.4% 42 10
Suicide attempt 389 16.2% 40 28
Blood glucose increased 379 15.7% 41 9
Anosognosia 374 15.5% 41 3
Blood prolactin abnormal 374 15.5% 41 3
Metabolic disorder 374 15.5% 41 3
Disturbance in social behaviour 371 15.4% 41 3
Personality change 340 14.1% 41 3
Condition aggravated 302 12.5% 39 49
Neutropenia 190 7.9% 70 108
Off label use 184 7.6% 82 139
Extrapyramidal disorder 164 6.8% 75 124
Psychotic disorder 163 6.8% 91 112
Fatigue 155 6.4% 70 111
Leukopenia 144 6.0% 71 91

Who Reports ZUCLOPENTHIXOL Side Effects? Age & Gender Data

Gender: 36.4% female, 63.6% male. Average age: 46.3 years. Most reports from: GB. View detailed demographics →

Is ZUCLOPENTHIXOL Getting Safer? Reports by Year

YearReportsDeathsHosp.
2001 1 0 0
2003 2 0 0
2004 1 0 0
2005 23 3 3
2006 4 2 0
2007 3 0 2
2008 6 1 1
2009 14 1 7
2010 9 1 6
2011 9 1 4
2012 11 0 8
2013 10 0 9
2014 56 14 45
2015 150 77 120
2016 55 2 17
2017 162 20 75
2018 118 8 72
2019 127 13 63
2020 102 4 75
2021 58 2 44
2022 54 4 33
2023 32 1 15
2024 86 6 61
2025 53 29 39

View full timeline →

What Is ZUCLOPENTHIXOL Used For?

IndicationReports
Product used for unknown indication 846
Schizophrenia 790
Psychotic disorder 147
Schizoaffective disorder 105
Agitation 47
Mania 39
Aggression 35
Bipolar disorder 35
Mental disorder 35
Hallucination, auditory 32

ZUCLOPENTHIXOL vs Alternatives: Which Is Safer?

ZUCLOPENTHIXOL vs ZUCLOPENTHIXOL DECANOATE ZUCLOPENTHIXOL vs ZURANOLONE ZUCLOPENTHIXOL vs ZYPREXA ZUCLOPENTHIXOL vs ZYTIGA ZUCLOPENTHIXOL vs ZYVOX ZUCLOPENTHIXOL vs 5-FLUOROURACIL ZUCLOPENTHIXOL vs 5-FU ZUCLOPENTHIXOL vs 6-ACETYLMORPHINE ZUCLOPENTHIXOL vs ABACAVIR ZUCLOPENTHIXOL vs ABACAVIR\DOLUTEGRAVIR\LAMIVUDINE

Official FDA Label for ZUCLOPENTHIXOL

Official prescribing information from the FDA-approved drug label.