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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Antibiotic prophylaxis: Which Medications Are Safest? (341 Drugs Compared)

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341 medications are used for Antibiotic prophylaxis, with 8,253 combined adverse event reports. The most reported drugs for Antibiotic prophylaxis are SULFAMETHOXAZOLE\TRIMETHOPRIM and CEFAZOLIN.

8,253
Total Reports
341
Drugs Used

All Medications for Antibiotic prophylaxis Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
SULFAMETHOXAZOLE\TRIMETHOPRIM - 1,107 5,777 19,426 14.9%
CEFAZOLIN Cefazolin 1,017 345 2,331 6.7%
VANCOMYCIN Vancomycin Hydrochloride 669 5,348 15,776 15.8%
CIPROFLOXACIN Ciprofloxacin 585 2,671 13,894 6.1%
AMOXICILLIN Amoxicillin and Clavulanate Potassium 505 1,212 11,721 4.0%
LEVOFLOXACIN Levofloxacin 416 2,747 13,832 6.8%
CEFUROXIME Cefuroxime sodium 401 439 2,274 8.4%
AMOXICILLIN\CLAVULANATE - 370 998 6,376 6.5%
CLINDAMYCIN XACIATO 331 986 5,320 5.8%
METRONIDAZOLE metronidazole 308 2,188 7,909 9.7%
PIPERACILLIN\TAZOBACTAM - 279 3,372 10,462 17.6%
ISONIAZID Isoniazid 268 1,028 3,141 13.5%
GENTAMICIN Gentamicin 234 947 2,865 14.4%
AMOXICILLIN\CLAVULANIC ACID - 222 885 5,097 8.4%
CEFTRIAXONE Ceftriaxone 221 2,926 9,596 15.1%
CHLORHEXIDINE Dyna-Hex 2 160 3,017 3,987 33.7%
MEROPENEM Meropenem 159 3,880 7,167 28.0%
AZITHROMYCIN AZITHROMYCIN 153 1,405 5,983 8.0%
AMPICILLIN Ampicillin and Sulbactam 144 482 1,227 13.2%
LINEZOLID Linezolid 124 2,952 7,491 16.4%

View all 341 drugs →

Most Reported Drugs for Antibiotic prophylaxis

#2 most reported
#3 most reported