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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Arthritis: Which Medications Are Safest? (600 Drugs Compared)

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600 medications are used for Arthritis, with 32,110 combined adverse event reports. The most reported drugs for Arthritis are DICLOFENAC and CELECOXIB.

32,110
Total Reports
600
Drugs Used

All Medications for Arthritis Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
DICLOFENAC Diclofenac Sodium Delayed Release 8,680 6,378 16,398 7.3%
CELECOXIB Celecoxib 3,685 4,470 9,081 14.1%
ACETAMINOPHEN Hydrocodone Bitartrate and Acetaminophen 1,860 30,085 50,046 22.0%
TOFACITINIB XELJANZ XR 1,832 7,847 21,976 5.0%
NAPROXEN Naproxen Sodium 1,656 5,127 12,849 9.7%
ETANERCEPT ENBREL 1,489 10,338 36,932 2.9%
ADALIMUMAB YUSIMRY 1,380 21,807 108,264 4.4%
METHOTREXATE Methotrexate 1,177 21,265 68,793 8.4%
IBUPROFEN equate ibuprofen 795 6,705 29,386 7.7%
PREGABALIN Pregabalin 717 8,959 22,920 8.8%
PREDNISONE prednisone 482 22,555 57,772 14.2%
APREMILAST Otezla 389 4,704 9,544 3.4%
MELOXICAM Meloxicam 379 1,042 2,502 12.0%
ABATACEPT ORENCIA 354 7,681 21,254 6.6%
INFLIXIMAB Renflexis 323 7,516 36,324 5.4%
GOLIMUMAB SIMPONI ARIA 300 4,866 15,471 7.0%
LEFLUNOMIDE Leflunomide 292 5,283 13,923 9.3%
GLUCOSAMINE - 289 484 952 35.5%
TOCILIZUMAB Tocilizumab-anoh 282 9,543 24,039 9.7%
CELEBREX - 257 33 122 2.0%

View all 600 drugs →

Most Reported Drugs for Arthritis

#1 most reported
#2 most reported
#3 most reported