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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Bipolar i disorder: Which Medications Are Safest? (226 Drugs Compared)

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226 medications are used for Bipolar i disorder, with 6,537 combined adverse event reports. The most reported drugs for Bipolar i disorder are ARIPIPRAZOLE and QUETIAPINE.

6,537
Total Reports
226
Drugs Used

All Medications for Bipolar i disorder Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
ARIPIPRAZOLE Aripiprazole 1,197 3,863 20,713 5.8%
QUETIAPINE Quetiapine 760 13,610 31,386 18.6%
CARIPRAZINE Vraylar 737 194 702 3.0%
LITHIUM Bestmade Natural Products Lithium Chloride (Lith Mur) 644 1,568 7,711 10.5%
OLANZAPINE Olanzapine 524 5,535 21,934 10.8%
LURASIDONE lurasidone hydrochloride 494 709 2,381 4.1%
RISPERIDONE Risperidone 494 4,120 18,771 5.2%
LAMOTRIGINE Lamotrigine ER 406 6,604 17,639 13.7%
LUMATEPERONE CAPLYTA 274 41 397 0.8%
PALIPERIDONE paliperidone 273 1,809 8,499 4.4%
DIVALPROEX Divalproex Sodium 180 478 4,169 4.2%
OLANZAPINE\SAMIDORPHAN L-MALATE - 165 14 116 1.1%
VALPROIC ACID Valproic Acid 160 2,667 8,183 13.3%
CLOZAPINE CLOZAPINE 129 15,347 41,887 16.1%
BREXPIPRAZOLE Rexulti 108 673 1,269 5.1%
CARBAMAZEPINE Carbamazepine 100 2,156 9,608 8.8%
HALOPERIDOL Haloperidol 92 1,882 7,393 11.8%
VENLAFAXINE Venlafaxine Hydrochloride 91 7,521 15,749 15.7%
CHLORPROMAZINE Chlorpromazine 89 671 1,793 17.0%
VALPROATE Valproate Sodium 83 1,000 6,625 6.3%

View all 226 drugs →

Most Reported Drugs for Bipolar i disorder

#1 most reported
#2 most reported
#3 most reported