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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Cluster headache: Which Medications Are Safest? (119 Drugs Compared)

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119 medications are used for Cluster headache, with 1,681 combined adverse event reports. The most reported drugs for Cluster headache are GALCANEZUMAB-GNLM and SUMATRIPTAN.

1,681
Total Reports
119
Drugs Used

All Medications for Cluster headache Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
GALCANEZUMAB-GNLM - 684 66 681 0.2%
SUMATRIPTAN sumatriptan succinate 302 305 1,580 1.7%
VERAPAMIL Verapamil Hydrochloride 150 2,630 3,576 28.2%
TOPIRAMATE Topiramate 124 3,527 7,098 12.3%
ERENUMAB-AOOE - 71 1,935 3,054 3.9%
LITHIUM Bestmade Natural Products Lithium Chloride (Lith Mur) 47 1,568 7,711 10.5%
PREGABALIN Pregabalin 38 8,959 22,920 8.8%
ACETAMINOPHEN\ASPIRIN\CAFFEINE - 36 155 438 1.3%
GABAPENTIN Gabapentin 28 11,101 16,499 14.9%
AMITRIPTYLINE AMITRIPTYLINE HYDROCHLORIDE 27 4,837 7,290 23.7%
PREDNISONE prednisone 26 22,555 57,772 14.2%
RIMEGEPANT NURTEC ODT 26 77 217 0.8%
OXYCODONE Oxycodone Hydrochloride 23 55,140 21,279 28.9%
CARBAMAZEPINE Carbamazepine 19 2,156 9,608 8.8%
FREMANEZUMAB-VFRM - 18 74 558 0.8%
DICLOFENAC Diclofenac Sodium Delayed Release 16 6,378 16,398 7.3%
ELETRIPTAN HYDROBROMIDE Eletriptan hydrobromide 14 12 271 0.6%
IBUPROFEN equate ibuprofen 14 6,705 29,386 7.7%
ONABOTULINUMTOXINA - 14 1,489 2,307 3.0%
TRAMADOL ConZip 13 14,555 19,235 19.2%

View all 119 drugs →

Most Reported Drugs for Cluster headache

#1 most reported
#2 most reported
#3 most reported