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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Depressed mood: Which Medications Are Safest? (133 Drugs Compared)

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133 medications are used for Depressed mood, with 2,098 combined adverse event reports. The most reported drugs for Depressed mood are SERTRALINE and CITALOPRAM HYDROBROMIDE.

2,098
Total Reports
133
Drugs Used

All Medications for Depressed mood Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
SERTRALINE Sertraline Hydrochloride 516 6,889 19,327 11.5%
CITALOPRAM HYDROBROMIDE Citalopram Hydrobromide 241 6,745 9,074 24.9%
MIRTAZAPINE Mirtazapine 217 5,410 11,495 18.9%
ESCITALOPRAM OXALATE Escitalopram 178 3,531 11,942 11.6%
FLUOXETINE Fluoxetine 177 5,534 11,247 17.7%
VENLAFAXINE Venlafaxine Hydrochloride 157 7,521 15,749 15.7%
PAROXETINE Paroxetine 134 2,854 8,171 13.3%
DULOXETINE Duloxetine Hydrochloride 97 4,044 10,622 7.7%
QUETIAPINE Quetiapine 61 13,610 31,386 18.6%
LAMOTRIGINE Lamotrigine ER 59 6,604 17,639 13.7%
ARIPIPRAZOLE Aripiprazole 45 3,863 20,713 5.8%
BUPROPION Bupropion Hydrochloride (XL) 42 8,577 10,246 24.1%
OLANZAPINE Olanzapine 37 5,535 21,934 10.8%
CITALOPRAM Citalopram 28 1,947 1,002 46.7%
VORTIOXETINE HYDROBROMIDE Trintellix 24 400 1,741 2.9%
RISPERIDONE Risperidone 23 4,120 18,771 5.2%
TRAZODONE Trazodone Hydrochloride 18 6,213 7,153 32.4%
LORAZEPAM Lorazepam 16 6,187 15,431 18.5%
ZOLPIDEM\ZOLPIDEM - 16 1,996 2,369 33.9%
ZOLPIDEM Zolpidem Tartrate 15 3,908 7,033 18.2%

View all 133 drugs →

Most Reported Drugs for Depressed mood

#1 most reported
#2 most reported
#3 most reported