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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Depressive symptom: Which Medications Are Safest? (129 Drugs Compared)

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129 medications are used for Depressive symptom, with 1,149 combined adverse event reports. The most reported drugs for Depressive symptom are SERTRALINE and MIRTAZAPINE.

1,149
Total Reports
129
Drugs Used

All Medications for Depressive symptom Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
SERTRALINE Sertraline Hydrochloride 189 6,889 19,327 11.5%
MIRTAZAPINE Mirtazapine 138 5,410 11,495 18.9%
ESCITALOPRAM OXALATE Escitalopram 136 3,531 11,942 11.6%
VENLAFAXINE Venlafaxine Hydrochloride 123 7,521 15,749 15.7%
FLUOXETINE Fluoxetine 84 5,534 11,247 17.7%
DULOXETINE Duloxetine Hydrochloride 79 4,044 10,622 7.7%
ARIPIPRAZOLE Aripiprazole 63 3,863 20,713 5.8%
PAROXETINE Paroxetine 59 2,854 8,171 13.3%
CITALOPRAM HYDROBROMIDE Citalopram Hydrobromide 57 6,745 9,074 24.9%
QUETIAPINE Quetiapine 57 13,610 31,386 18.6%
OLANZAPINE Olanzapine 52 5,535 21,934 10.8%
ALPRAZOLAM Alprazolam 46 16,072 15,996 33.2%
LAMOTRIGINE Lamotrigine ER 45 6,604 17,639 13.7%
VORTIOXETINE HYDROBROMIDE Trintellix 42 400 1,741 2.9%
BUPROPION Bupropion Hydrochloride (XL) 41 8,577 10,246 24.1%
DIAZEPAM Diazepam 39 12,045 13,635 31.6%
LURASIDONE lurasidone hydrochloride 34 709 2,381 4.1%
RISPERIDONE Risperidone 28 4,120 18,771 5.2%
TRAZODONE Trazodone Hydrochloride 25 6,213 7,153 32.4%
ZOLPIDEM Zolpidem Tartrate 16 3,908 7,033 18.2%

View all 129 drugs →

Most Reported Drugs for Depressive symptom

#1 most reported
#2 most reported
#3 most reported