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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Detoxification: Which Medications Are Safest? (71 Drugs Compared)

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71 medications are used for Detoxification, with 189 combined adverse event reports. The most reported drugs for Detoxification are METHADONE and BUPRENORPHINE\NALOXONE.

189
Total Reports
71
Drugs Used

All Medications for Detoxification Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
METHADONE METHADONE HYDROCHLORIDE 34 10,719 5,514 40.8%
BUPRENORPHINE\NALOXONE - 10 1,119 2,872 5.2%
CHOLESTYRAMINE cholestyramine powder for suspension 10 117 445 5.0%
LOPERAMIDE Anti-diarrheal 10 1,551 4,298 8.6%
MAGNESIUM citroma 10 1,878 4,530 19.3%
PREGABALIN Pregabalin 9 8,959 22,920 8.8%
SODIUM Sodium Chloride 9 1,550 6,212 6.6%
BUPRENORPHINE Buprenorphine and Naloxone 8 25,813 9,467 31.5%
LEUCOVORIN LEUCOVORIN CALCIUM 8 3,932 10,039 15.7%
CALCIUM\POTASSIUM\SODIUM - 7 38 108 17.2%
CHLORDIAZEPOXIDE Chlordiazepoxide Hydrochloride 7 493 357 48.6%
DIAZEPAM Diazepam 7 12,045 13,635 31.6%
MESNA mesna 7 1,029 2,155 21.0%
BACLOFEN BACLOFEN 6 2,958 8,773 11.5%
BUPROPION Bupropion Hydrochloride (XL) 6 8,577 10,246 24.1%
LORAZEPAM Lorazepam 6 6,187 15,431 18.5%
COLESEVELAM Colesevelam hydrochloride 5 30 265 0.9%
NALOXONE Naloxone Hydrochloride 5 779 1,033 27.2%
NALTREXONE NALTREXONE HYDROCHLORIDE 5 1,106 2,843 4.3%

View all 71 drugs →

Most Reported Drugs for Detoxification

#1 most reported
#2 most reported
#3 most reported