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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Drug use disorder: Which Medications Are Safest? (161 Drugs Compared)

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161 medications are used for Drug use disorder, with 6,016 combined adverse event reports. The most reported drugs for Drug use disorder are BUPRENORPHINE\NALOXONE and BUPRENORPHINE.

6,016
Total Reports
161
Drugs Used

All Medications for Drug use disorder Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
BUPRENORPHINE\NALOXONE - 1,817 1,119 2,872 5.2%
BUPRENORPHINE Buprenorphine and Naloxone 1,772 25,813 9,467 31.5%
NALTREXONE NALTREXONE HYDROCHLORIDE 1,500 1,106 2,843 4.3%
METHADONE METHADONE HYDROCHLORIDE 512 10,719 5,514 40.8%
OXYCODONE Oxycodone Hydrochloride 209 55,140 21,279 28.9%
MORPHINE Morphine Sulfate 82 38,212 17,386 31.7%
NALOXONE Naloxone Hydrochloride 64 779 1,033 27.2%
PROPOFOL Propofol 52 1,970 6,577 12.3%
HYDROMORPHONE Hydromorphone Hydrochloride 49 28,491 10,395 34.1%
LOPERAMIDE Anti-diarrheal 46 1,551 4,298 8.6%
TRAMADOL ConZip 46 14,555 19,235 19.2%
ALPRAZOLAM Alprazolam 42 16,072 15,996 33.2%
FENTANYL FENTANYL 38 42,491 15,153 45.0%
GABAPENTIN Gabapentin 38 11,101 16,499 14.9%
DIAZEPAM Diazepam 36 12,045 13,635 31.6%
DIAMORPHINE - 29 4,735 1,656 52.6%
BUPROPION Bupropion Hydrochloride (XL) 28 8,577 10,246 24.1%
PREGABALIN Pregabalin 27 8,959 22,920 8.8%
COCAINE NUMBRINO 24 8,171 3,863 57.5%
ZOLPIDEM Zolpidem Tartrate 24 3,908 7,033 18.2%

View all 161 drugs →

Most Reported Drugs for Drug use disorder

#1 most reported
#2 most reported
#3 most reported