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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Fibromyalgia: Which Medications Are Safest? (434 Drugs Compared)

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434 medications are used for Fibromyalgia, with 23,503 combined adverse event reports. The most reported drugs for Fibromyalgia are PREGABALIN and DULOXETINE.

23,503
Total Reports
434
Drugs Used

All Medications for Fibromyalgia Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
PREGABALIN Pregabalin 11,373 8,959 22,920 8.8%
DULOXETINE Duloxetine Hydrochloride 2,876 4,044 10,622 7.7%
GABAPENTIN Gabapentin 1,838 11,101 16,499 14.9%
SODIUM OXYBATE sodium oxybate 1,116 537 6,147 0.9%
LYRICA - 884 142 504 2.7%
MORPHINE Morphine Sulfate 540 38,212 17,386 31.7%
CYCLOBENZAPRINE Cyclobenzaprine hydrochloride 360 3,862 2,820 42.2%
MILNACIPRAN Savella 349 120 274 8.6%
ETANERCEPT ENBREL 327 10,338 36,932 2.9%
FENTANYL FENTANYL 302 42,491 15,153 45.0%
TRAMADOL ConZip 269 14,555 19,235 19.2%
ADALIMUMAB YUSIMRY 265 21,807 108,264 4.4%
OXYCODONE Oxycodone Hydrochloride 265 55,140 21,279 28.9%
AMITRIPTYLINE AMITRIPTYLINE HYDROCHLORIDE 224 4,837 7,290 23.7%
CELECOXIB Celecoxib 222 4,470 9,081 14.1%
DICLOFENAC Diclofenac Sodium Delayed Release 209 6,378 16,398 7.3%
TOFACITINIB XELJANZ XR 198 7,847 21,976 5.0%
ACETAMINOPHEN Hydrocodone Bitartrate and Acetaminophen 197 30,085 50,046 22.0%
BUPRENORPHINE Buprenorphine and Naloxone 190 25,813 9,467 31.5%
CARBAMAZEPINE Carbamazepine 181 2,156 9,608 8.8%

View all 434 drugs →

Most Reported Drugs for Fibromyalgia

#1 most reported
#2 most reported
#3 most reported