Skip to content
Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Fluid retention: Which Medications Are Safest? (129 Drugs Compared)

Boost Your Natural Energy & Metabolism

Mitolyn — 6 exotic plants to unlock your body's fat-burning power. 90-day guarantee.

Try Mitolyn Now

129 medications are used for Fluid retention, with 1,609 combined adverse event reports. The most reported drugs for Fluid retention are FUROSEMIDE and TOLVAPTAN.

1,609
Total Reports
129
Drugs Used

All Medications for Fluid retention Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
FUROSEMIDE Furosemide 786 6,131 30,446 11.8%
TOLVAPTAN Jynarque 300 1,709 2,467 19.0%
SPIRONOLACTONE spironolactone 142 1,809 11,611 8.6%
HYDROCHLOROTHIAZIDE Irbesartan and Hydrochlorothiazide 97 2,177 10,714 10.4%
BUMETANIDE Bumetanide 49 264 1,240 12.3%
METOLAZONE Metolazone 42 202 692 17.4%
TORSEMIDE Torsemide 39 656 6,070 8.0%
HYDROCHLOROTHIAZIDE\TRIAMTERENE - 19 136 333 11.7%
SAMSCA - 18 53 34 22.5%
SACUBITRIL\VALSARTAN - 17 15,665 18,923 14.1%
POTASSIUM POTASSIUM CITRATE 10 2,094 5,157 17.5%
CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM - 8 23,230 39,850 24.7%
CALCIUM\ICODEXTRIN\MAGNESIUM\SODIUM\SODIUM - 8 6,471 8,428 32.6%
CHLORTHALIDONE Chlorthalidone 8 147 894 8.5%
HYDROCHLOROTHIAZIDE\VALSARTAN - 8 634 2,300 9.3%
HYDROCHLOROTHIAZIDE\LISINOPRIL - 7 265 1,136 10.1%
HYDROCHLOROTHIAZIDE\OLMESARTAN MEDOXOMIL - 7 95 3,369 1.6%
AZOSEMIDE - 6 93 290 19.6%
LISINOPRIL Lisinopril 6 4,382 13,362 11.9%
ETHACRYNIC ACID ethacrynic acid 5 7 62 4.8%

View all 129 drugs →

Most Reported Drugs for Fluid retention

#1 most reported
#2 most reported
#3 most reported