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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Heavy menstrual bleeding: Which Medications Are Safest? (70 Drugs Compared)

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70 medications are used for Heavy menstrual bleeding, with 3,785 combined adverse event reports. The most reported drugs for Heavy menstrual bleeding are LEVONORGESTREL and ESTRADIOL\NORETHINDRONE\RELUGOLIX.

3,785
Total Reports
70
Drugs Used

All Medications for Heavy menstrual bleeding Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
LEVONORGESTREL Mirena 2,888 142 6,322 0.1%
ESTRADIOL\NORETHINDRONE\RELUGOLIX - 239 2 81 0.1%
DROSPIRENONE Angeliq 81 9 146 0.3%
TRANEXAMIC ACID Tranexamic Acid 63 319 1,225 10.3%
ELAGOLIX\ESTRADIOL\NORETHINDRONE - 50 1 56 0.2%
ETONOGESTREL Nexplanon 48 79 1,438 0.2%
ETHINYL ESTRADIOL\LEVONORGESTREL - 44 104 1,046 2.3%
MEDROXYPROGESTERONE Provera 44 135 831 1.6%
ETHINYL ESTRADIOL\NORETHINDRONE - 36 85 418 1.9%
DROSPIRENONE\ETHINYL ESTRADIOL - 35 212 2,702 3.3%
RELUGOLIX Orgovyx 32 958 1,699 4.6%
NORETHINDRONE ERRIN 28 26 261 1.3%
DIENOGEST\ESTRADIOL - 25 6 143 0.9%
LEUPROLIDE Fensolvi 21 11,858 10,499 16.7%
ETHINYL ESTRADIOL\NORELGESTROMIN - 20 12 78 0.2%
FERRIC CARBOXYMALTOSE Injectafer 17 205 1,670 2.5%
ELAGOLIX Orilissa 9 5 299 0.1%
ETHINYL ESTRADIOL\ETONOGESTREL - 8 130 3,386 1.1%
PROGESTERONE Progesterone 8 222 1,143 4.0%
DUPILUMAB Dupixent 7 1,536 17,008 0.4%

View all 70 drugs →

Most Reported Drugs for Heavy menstrual bleeding

#1 most reported
#3 most reported