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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Hyperhidrosis: Which Medications Are Safest? (132 Drugs Compared)

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132 medications are used for Hyperhidrosis, with 1,625 combined adverse event reports. The most reported drugs for Hyperhidrosis are ONABOTULINUMTOXINA and GLYCOPYRRONIUM.

1,625
Total Reports
132
Drugs Used

All Medications for Hyperhidrosis Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
ONABOTULINUMTOXINA - 508 1,489 2,307 3.0%
GLYCOPYRRONIUM Qbrexza 497 37 210 2.8%
GLYCOPYRROLATE GLYCOPYRROLATE 52 392 1,392 8.5%
OXYBUTYNIN Oxybutynin Chloride 43 350 1,113 4.5%
ABOBOTULINUMTOXINA - 38 109 406 1.9%
BOTOX - 31 19 51 2.2%
ESTROGENS, CONJUGATED Premarin 31 171 892 1.9%
BOTULINUM TOXIN TYPE A Jeuveau 27 1,288 1,536 34.4%
ESTROGENS, CONJUGATED\MEDROXYPROGESTERONE - 23 22 122 1.3%
ACETAMINOPHEN Hydrocodone Bitartrate and Acetaminophen 22 30,085 50,046 22.0%
ALUMINUM Unda 3 21 5 19 4.7%
ESTRADIOL Estradiol 21 267 1,953 0.9%
FEZOLINETANT VEOZAH 17 1 32 0.1%
SOFPIRONIUM Sofdra 17 0 1 N/A
IBUPROFEN equate ibuprofen 15 6,705 29,386 7.7%
INCOBOTULINUMTOXINA - 15 76 150 1.6%
ALUMINUM ZIRCONIUM TETRACHLOROHYDREX GLY Dove Clinical Care 14 0 10 N/A
DUPILUMAB Dupixent 13 1,536 17,008 0.4%
GABAPENTIN Gabapentin 12 11,101 16,499 14.9%
CLONIDINE Clonidine hydrochloride 11 2,401 3,920 19.1%

View all 132 drugs →

Most Reported Drugs for Hyperhidrosis

#1 most reported
#2 most reported
#3 most reported