Irritability: Which Medications Are Safest? (150 Drugs Compared)
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150 medications are used for Irritability, with 1,152 combined adverse event reports. The most reported drugs for Irritability are ARIPIPRAZOLE and RISPERIDONE.
1,152
Total Reports
150
Drugs Used
All Medications for Irritability Ranked by Safety Reports
| Drug | Brand | Reports | Deaths (all) | Hosp. (all) | Death Rate |
|---|---|---|---|---|---|
| ARIPIPRAZOLE | Aripiprazole | 326 | 3,863 | 20,713 | 5.8% |
| RISPERIDONE | Risperidone | 254 | 4,120 | 18,771 | 5.2% |
| QUETIAPINE | Quetiapine | 64 | 13,610 | 31,386 | 18.6% |
| BREXPIPRAZOLE | Rexulti | 53 | 673 | 1,269 | 5.1% |
| OLANZAPINE | Olanzapine | 36 | 5,535 | 21,934 | 10.8% |
| HOMEOPATHICS | - | 27 | 30 | 298 | 2.8% |
| SERTRALINE | Sertraline Hydrochloride | 26 | 6,889 | 19,327 | 11.5% |
| DULOXETINE | Duloxetine Hydrochloride | 22 | 4,044 | 10,622 | 7.7% |
| ACETAMINOPHEN | Hydrocodone Bitartrate and Acetaminophen | 19 | 30,085 | 50,046 | 22.0% |
| ESTRADIOL\NORETHINDRONE | - | 18 | 27 | 275 | 0.6% |
| ESCITALOPRAM OXALATE | Escitalopram | 17 | 3,531 | 11,942 | 11.6% |
| ESTRADIOL | Estradiol | 17 | 267 | 1,953 | 0.9% |
| CLOZAPINE | CLOZAPINE | 15 | 15,347 | 41,887 | 16.1% |
| GABAPENTIN | Gabapentin | 14 | 11,101 | 16,499 | 14.9% |
| CLONAZEPAM | Clonazepam | 12 | 8,488 | 12,506 | 21.5% |
| FLUOXETINE | Fluoxetine | 12 | 5,534 | 11,247 | 17.7% |
| LAMOTRIGINE | Lamotrigine ER | 12 | 6,604 | 17,639 | 13.7% |
| CLONIDINE | Clonidine hydrochloride | 11 | 2,401 | 3,920 | 19.1% |
| HALOPERIDOL | Haloperidol | 11 | 1,882 | 7,393 | 11.8% |
| DESVENLAFAXINE | Desvenlafaxine Succinate | 10 | 447 | 1,093 | 5.0% |