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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Irritable bowel syndrome: Which Medications Are Safest? (283 Drugs Compared)

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283 medications are used for Irritable bowel syndrome, with 8,731 combined adverse event reports. The most reported drugs for Irritable bowel syndrome are LINACLOTIDE and ELUXADOLINE.

8,731
Total Reports
283
Drugs Used

All Medications for Irritable bowel syndrome Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
LINACLOTIDE Linzess 2,493 358 756 2.7%
ELUXADOLINE Viberzi 1,233 37 413 1.6%
RIFAXIMIN XIFAXAN 964 5,009 4,847 36.1%
LOPERAMIDE Anti-diarrheal 541 1,551 4,298 8.6%
DIMETHICONE\LOPERAMIDE - 365 8 55 0.1%
TENAPANOR IBSRELA 332 332 568 17.2%
RANITIDINE Ranitidine 304 26,824 7,673 6.4%
POLYETHYLENE GLYCOL 3350 Polyethylene Glycol 3350, Sodium Chloride, Sodium Bicarbonate and Potassium Chloride - Unflavored 299 478 1,116 1.3%
PLECANATIDE Trulance Immediate release 199 45 50 4.7%
COLESEVELAM Colesevelam hydrochloride 149 30 265 0.9%
ADALIMUMAB YUSIMRY 143 21,807 108,264 4.4%
DICYCLOMINE Dicyclomine Hydrochloride 130 179 261 16.0%
CHOLESTYRAMINE cholestyramine powder for suspension 94 117 445 5.0%
PRUCALOPRIDE Prucalopride 93 33 199 2.3%
HYOSCYAMINE hyoscyamine sulfate 92 71 165 11.4%
MESALAMINE Mesalamine 75 1,744 6,015 9.0%
LINZESS - 74 2 15 0.7%
ATROPINE\DIPHENOXYLATE - 70 100 450 5.3%
LUBIPROSTONE Amitza 64 118 332 9.7%
OMEPRAZOLE omeprazole sodium bicarbonate 60 8,515 19,847 9.8%

View all 283 drugs →

Most Reported Drugs for Irritable bowel syndrome

#1 most reported
#2 most reported
#3 most reported