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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Joint stiffness: Which Medications Are Safest? (66 Drugs Compared)

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66 medications are used for Joint stiffness, with 220 combined adverse event reports. The most reported drugs for Joint stiffness are DICLOFENAC and NAPROXEN.

220
Total Reports
66
Drugs Used

All Medications for Joint stiffness Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
DICLOFENAC Diclofenac Sodium Delayed Release 89 6,378 16,398 7.3%
NAPROXEN Naproxen Sodium 57 5,127 12,849 9.7%
ADALIMUMAB YUSIMRY 51 21,807 108,264 4.4%
IBUPROFEN equate ibuprofen 49 6,705 29,386 7.7%
HYDROXYCHLOROQUINE HYDROXYCHLOROQUINE SULFATE 48 6,506 16,905 9.8%
LEFLUNOMIDE Leflunomide 48 5,283 13,923 9.3%
METHOTREXATE Methotrexate 46 21,265 68,793 8.4%
GOLD Aurum Met 45 914 1,724 22.1%
ASPIRIN Aspirin 44 13,029 53,089 14.1%
ETANERCEPT ENBREL 44 10,338 36,932 2.9%
CLOPIDOGREL BISULFATE Clopidogrel 16 5,327 24,774 11.6%
ASPIRIN\CLOPIDOGREL - 11 80 286 18.5%
DICLOFENAC DIETHYLAMINE - 11 1,717 1,993 45.8%
TOFACITINIB XELJANZ XR 11 7,847 21,976 5.0%
ACETAMINOPHEN Hydrocodone Bitartrate and Acetaminophen 9 30,085 50,046 22.0%
CELECOXIB Celecoxib 8 4,470 9,081 14.1%
GOLD THIOMALATE - 7 1,451 2,420 32.5%
IBUPROFEN\PSEUDOEPHEDRINE - 7 5 103 0.6%
DICLOFENAC\DICLOFENAC - 6 1,210 1,771 35.9%
HYDROXYCHLOROQUINE DIPHOSPHATE - 5 134 438 7.2%

View all 66 drugs →

Most Reported Drugs for Joint stiffness

#1 most reported
#2 most reported
#3 most reported