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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Knee arthroplasty: Which Medications Are Safest? (132 Drugs Compared)

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132 medications are used for Knee arthroplasty, with 1,705 combined adverse event reports. The most reported drugs for Knee arthroplasty are RIVAROXABAN and BUPIVACAINE.

1,705
Total Reports
132
Drugs Used

All Medications for Knee arthroplasty Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
RIVAROXABAN Rivaroxaban 991 19,233 70,513 14.7%
BUPIVACAINE Bupivacaine Hydrochloride 137 466 2,367 4.1%
XARELTO - 77 395 1,703 11.3%
DICLOFENAC Diclofenac Sodium Delayed Release 63 6,378 16,398 7.3%
OXYCODONE Oxycodone Hydrochloride 44 55,140 21,279 28.9%
ENOXAPARIN Enoxaparin Sodium 28 3,423 10,898 13.7%
APIXABAN ELIQUIS 26 27,970 42,651 17.5%
CELECOXIB Celecoxib 23 4,470 9,081 14.1%
TRAMADOL ConZip 23 14,555 19,235 19.2%
ACETAMINOPHEN\HYDROCODONE - 19 31,727 6,901 29.1%
ACETAMINOPHEN\OXYCODONE - 18 31,342 7,703 31.5%
TRANEXAMIC ACID Tranexamic Acid 18 319 1,225 10.3%
VANCOMYCIN Vancomycin Hydrochloride 18 5,348 15,776 15.8%
FENTANYL FENTANYL 17 42,491 15,153 45.0%
ACETAMINOPHEN Hydrocodone Bitartrate and Acetaminophen 15 30,085 50,046 22.0%
BUPIVACAINE\MELOXICAM - 15 2 11 1.1%
PREGABALIN Pregabalin 15 8,959 22,920 8.8%
MORPHINE Morphine Sulfate 14 38,212 17,386 31.7%
DABIGATRAN ETEXILATE dabigatran etexilate 13 5,806 21,235 15.7%
GENTAMICIN Gentamicin 13 947 2,865 14.4%

View all 132 drugs →

Most Reported Drugs for Knee arthroplasty

#1 most reported
#2 most reported
#3 most reported