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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Migraine: Which Medications Are Safest? (878 Drugs Compared)

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878 medications are used for Migraine, with 86,847 combined adverse event reports. The most reported drugs for Migraine are ERENUMAB-AOOE and GALCANEZUMAB-GNLM.

86,847
Total Reports
878
Drugs Used

All Medications for Migraine Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
ERENUMAB-AOOE - 19,137 1,935 3,054 3.9%
GALCANEZUMAB-GNLM - 11,124 66 681 0.2%
SUMATRIPTAN sumatriptan succinate 8,854 305 1,580 1.7%
ONABOTULINUMTOXINA - 6,443 1,489 2,307 3.0%
TOPIRAMATE Topiramate 5,515 3,527 7,098 12.3%
EPTINEZUMAB-JJMR - 4,979 42 438 0.6%
ACETAMINOPHEN\ASPIRIN\CAFFEINE - 4,879 155 438 1.3%
RIMEGEPANT NURTEC ODT 4,068 77 217 0.8%
FREMANEZUMAB-VFRM - 3,223 74 558 0.8%
PROPRANOLOL Propranolol Hydrochloride 1,982 3,221 4,912 16.6%
IBUPROFEN equate ibuprofen 1,944 6,705 29,386 7.7%
ATOGEPANT Qulipta 1,801 46 277 1.0%
CANDESARTAN - 1,786 1,899 5,063 21.0%
ACETAMINOPHEN Hydrocodone Bitartrate and Acetaminophen 1,372 30,085 50,046 22.0%
RIZATRIPTAN RIZATRIPTAN BENZOATE 1,365 68 479 2.3%
UBROGEPANT UBRELVY 1,318 49 145 1.9%
ELETRIPTAN HYDROBROMIDE Eletriptan hydrobromide 1,269 12 271 0.6%
ATOMOXETINE Atomoxetine 1,129 1,373 1,834 14.9%
DICLOFENAC Diclofenac Sodium Delayed Release 1,124 6,378 16,398 7.3%
ERENUMAB AIMOVIG 897 363 498 30.7%

View all 878 drugs →

Most Reported Drugs for Migraine

#1 most reported
#2 most reported
#3 most reported