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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Migraine without aura: Which Medications Are Safest? (123 Drugs Compared)

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123 medications are used for Migraine without aura, with 2,072 combined adverse event reports. The most reported drugs for Migraine without aura are ERENUMAB-AOOE and EPTINEZUMAB-JJMR.

2,072
Total Reports
123
Drugs Used

All Medications for Migraine without aura Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
ERENUMAB-AOOE - 858 1,935 3,054 3.9%
EPTINEZUMAB-JJMR - 194 42 438 0.6%
ONABOTULINUMTOXINA - 168 1,489 2,307 3.0%
FREMANEZUMAB-VFRM - 162 74 558 0.8%
DICLOFENAC Diclofenac Sodium Delayed Release 140 6,378 16,398 7.3%
SUMATRIPTAN sumatriptan succinate 92 305 1,580 1.7%
TOPIRAMATE Topiramate 79 3,527 7,098 12.3%
GABAPENTIN Gabapentin 52 11,101 16,499 14.9%
GALCANEZUMAB-GNLM - 48 66 681 0.2%
DUPILUMAB Dupixent 27 1,536 17,008 0.4%
ELETRIPTAN HYDROBROMIDE Eletriptan hydrobromide 21 12 271 0.6%
ERENUMAB AIMOVIG 21 363 498 30.7%
PREGABALIN Pregabalin 21 8,959 22,920 8.8%
ZOLMITRIPTAN Zolmitriptan 19 44 378 2.7%
AMITRIPTYLINE AMITRIPTYLINE HYDROCHLORIDE 18 4,837 7,290 23.7%
IBUPROFEN equate ibuprofen 18 6,705 29,386 7.7%
METOPROLOL metoprolol succinate 18 6,575 15,925 15.9%
RIZATRIPTAN RIZATRIPTAN BENZOATE 18 68 479 2.3%
DIHYDROERGOTAMINE Dihydroergotamine Mesylate 17 13 73 1.2%
VALPROIC ACID Valproic Acid 17 2,667 8,183 13.3%

View all 123 drugs →

Most Reported Drugs for Migraine without aura

#1 most reported
#2 most reported
#3 most reported