Skip to content
Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Muscle spasms: Which Medications Are Safest? (454 Drugs Compared)

Boost Your Natural Energy & Metabolism

Mitolyn — 6 exotic plants to unlock your body's fat-burning power. 90-day guarantee.

Try Mitolyn Now

454 medications are used for Muscle spasms, with 6,188 combined adverse event reports. The most reported drugs for Muscle spasms are BACLOFEN and TIZANIDINE.

6,188
Total Reports
454
Drugs Used

All Medications for Muscle spasms Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
BACLOFEN BACLOFEN 824 2,958 8,773 11.5%
TIZANIDINE Tizanidne hydrochloride 406 1,068 1,764 19.3%
ONABOTULINUMTOXINA - 338 1,489 2,307 3.0%
CYCLOBENZAPRINE Cyclobenzaprine hydrochloride 328 3,862 2,820 42.2%
DIAZEPAM Diazepam 291 12,045 13,635 31.6%
PREGABALIN Pregabalin 290 8,959 22,920 8.8%
IBUPROFEN equate ibuprofen 277 6,705 29,386 7.7%
DICLOFENAC Diclofenac Sodium Delayed Release 242 6,378 16,398 7.3%
GABAPENTIN Gabapentin 227 11,101 16,499 14.9%
QUININE Chininum sulphuricum 204 961 526 49.6%
ACETAMINOPHEN Hydrocodone Bitartrate and Acetaminophen 193 30,085 50,046 22.0%
NAPROXEN Naproxen Sodium 150 5,127 12,849 9.7%
METHOCARBAMOL Methocarbamol Tablets, USP, 500 mg 148 546 816 24.8%
LORAZEPAM Lorazepam 142 6,187 15,431 18.5%
METAXALONE Metaxalone 133 464 175 32.0%
CARISOPRODOL CARISOPRODOL 113 1,332 432 50.1%
CLONAZEPAM Clonazepam 99 8,488 12,506 21.5%
DIMETHICONE\LOPERAMIDE - 80 8 55 0.1%
ACETAMINOPHEN\IBUPROFEN - 73 21 59 0.7%
LIDOCAINE Burn Relief 66 1,738 5,570 7.6%

View all 454 drugs →

Most Reported Drugs for Muscle spasms

#1 most reported
#2 most reported
#3 most reported