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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Muscle tightness: Which Medications Are Safest? (61 Drugs Compared)

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61 medications are used for Muscle tightness, with 244 combined adverse event reports. The most reported drugs for Muscle tightness are ONABOTULINUMTOXINA and BACLOFEN.

244
Total Reports
61
Drugs Used

All Medications for Muscle tightness Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
ONABOTULINUMTOXINA - 31 1,489 2,307 3.0%
BACLOFEN BACLOFEN 23 2,958 8,773 11.5%
TIZANIDINE Tizanidne hydrochloride 22 1,068 1,764 19.3%
DICLOFENAC Diclofenac Sodium Delayed Release 16 6,378 16,398 7.3%
CYCLOBENZAPRINE Cyclobenzaprine hydrochloride 12 3,862 2,820 42.2%
PREGABALIN Pregabalin 10 8,959 22,920 8.8%
CLONAZEPAM Clonazepam 9 8,488 12,506 21.5%
GABAPENTIN Gabapentin 9 11,101 16,499 14.9%
IBUPROFEN equate ibuprofen 8 6,705 29,386 7.7%
METAXALONE Metaxalone 8 464 175 32.0%
ACETAMINOPHEN\IBUPROFEN - 7 21 59 0.7%
DIAZEPAM Diazepam 7 12,045 13,635 31.6%
METHOCARBAMOL Methocarbamol Tablets, USP, 500 mg 7 546 816 24.8%
NAPROXEN Naproxen Sodium 6 5,127 12,849 9.7%
CHLORZOXAZONE CHLORZOXAZONE 5 52 126 12.2%

View all 61 drugs →

Most Reported Drugs for Muscle tightness

#1 most reported
#2 most reported
#3 most reported