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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Musculoskeletal pain: Which Medications Are Safest? (250 Drugs Compared)

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250 medications are used for Musculoskeletal pain, with 3,618 combined adverse event reports. The most reported drugs for Musculoskeletal pain are DICLOFENAC and BACLOFEN.

3,618
Total Reports
250
Drugs Used

All Medications for Musculoskeletal pain Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
DICLOFENAC Diclofenac Sodium Delayed Release 719 6,378 16,398 7.3%
BACLOFEN BACLOFEN 364 2,958 8,773 11.5%
IBUPROFEN equate ibuprofen 331 6,705 29,386 7.7%
ACETAMINOPHEN Hydrocodone Bitartrate and Acetaminophen 245 30,085 50,046 22.0%
NAPROXEN Naproxen Sodium 229 5,127 12,849 9.7%
LIDOCAINE Burn Relief 199 1,738 5,570 7.6%
PREGABALIN Pregabalin 184 8,959 22,920 8.8%
DULOXETINE Duloxetine Hydrochloride 163 4,044 10,622 7.7%
CELECOXIB Celecoxib 120 4,470 9,081 14.1%
OXYCODONE Oxycodone Hydrochloride 108 55,140 21,279 28.9%
GABAPENTIN Gabapentin 101 11,101 16,499 14.9%
TRAMADOL ConZip 94 14,555 19,235 19.2%
FENTANYL FENTANYL 83 42,491 15,153 45.0%
BUPRENORPHINE Buprenorphine and Naloxone 48 25,813 9,467 31.5%
MELOXICAM Meloxicam 39 1,042 2,502 12.0%
METHYLPREDNISOLONE Medroloan II SUIK 34 12,828 26,552 20.1%
MORPHINE Morphine Sulfate 33 38,212 17,386 31.7%
ACETAMINOPHEN\OXYCODONE - 31 31,342 7,703 31.5%
KETOPROFEN Orudis 31 393 2,947 7.1%
DICLOFENAC EPOLAMINE Diclofenac Epolamine 29 31 171 1.9%

View all 250 drugs →

Most Reported Drugs for Musculoskeletal pain

#1 most reported
#2 most reported
#3 most reported