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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Musculoskeletal stiffness: Which Medications Are Safest? (151 Drugs Compared)

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151 medications are used for Musculoskeletal stiffness, with 1,004 combined adverse event reports. The most reported drugs for Musculoskeletal stiffness are DICLOFENAC and PROCYCLIDINE.

1,004
Total Reports
151
Drugs Used

All Medications for Musculoskeletal stiffness Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
DICLOFENAC Diclofenac Sodium Delayed Release 182 6,378 16,398 7.3%
PROCYCLIDINE - 149 85 430 12.8%
OLANZAPINE Olanzapine 73 5,535 21,934 10.8%
IBUPROFEN equate ibuprofen 61 6,705 29,386 7.7%
NAPROXEN Naproxen Sodium 61 5,127 12,849 9.7%
TOFACITINIB XELJANZ XR 47 7,847 21,976 5.0%
BACLOFEN BACLOFEN 44 2,958 8,773 11.5%
ACETAMINOPHEN Hydrocodone Bitartrate and Acetaminophen 41 30,085 50,046 22.0%
CELECOXIB Celecoxib 36 4,470 9,081 14.1%
PREGABALIN Pregabalin 36 8,959 22,920 8.8%
METHOTREXATE Methotrexate 23 21,265 68,793 8.4%
TIZANIDINE Tizanidne hydrochloride 18 1,068 1,764 19.3%
ACETAMINOPHEN\IBUPROFEN - 17 21 59 0.7%
DALFAMPRIDINE Dalfampridine 17 1,482 7,813 2.6%
ONABOTULINUMTOXINA - 15 1,489 2,307 3.0%
GABAPENTIN Gabapentin 14 11,101 16,499 14.9%
METHYLPREDNISOLONE Medroloan II SUIK 11 12,828 26,552 20.1%
CYCLOBENZAPRINE Cyclobenzaprine hydrochloride 10 3,862 2,820 42.2%
DIAZEPAM Diazepam 10 12,045 13,635 31.6%
ADALIMUMAB YUSIMRY 9 21,807 108,264 4.4%

View all 151 drugs →

Most Reported Drugs for Musculoskeletal stiffness

#1 most reported
#2 most reported
#3 most reported