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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Pain in extremity: Which Medications Are Safest? (493 Drugs Compared)

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493 medications are used for Pain in extremity, with 10,716 combined adverse event reports. The most reported drugs for Pain in extremity are PREGABALIN and DICLOFENAC.

10,716
Total Reports
493
Drugs Used

All Medications for Pain in extremity Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
PREGABALIN Pregabalin 2,326 8,959 22,920 8.8%
DICLOFENAC Diclofenac Sodium Delayed Release 1,523 6,378 16,398 7.3%
ACETAMINOPHEN Hydrocodone Bitartrate and Acetaminophen 1,142 30,085 50,046 22.0%
GABAPENTIN Gabapentin 1,025 11,101 16,499 14.9%
IBUPROFEN equate ibuprofen 759 6,705 29,386 7.7%
NAPROXEN Naproxen Sodium 362 5,127 12,849 9.7%
OXYCODONE Oxycodone Hydrochloride 346 55,140 21,279 28.9%
TRAMADOL ConZip 291 14,555 19,235 19.2%
FENTANYL FENTANYL 228 42,491 15,153 45.0%
LIDOCAINE Burn Relief 221 1,738 5,570 7.6%
MORPHINE Morphine Sulfate 201 38,212 17,386 31.7%
CELECOXIB Celecoxib 195 4,470 9,081 14.1%
DULOXETINE Duloxetine Hydrochloride 190 4,044 10,622 7.7%
ACETAMINOPHEN\HYDROCODONE - 147 31,727 6,901 29.1%
BUPRENORPHINE Buprenorphine and Naloxone 111 25,813 9,467 31.5%
LYRICA - 109 142 504 2.7%
HYDROMORPHONE Hydromorphone Hydrochloride 91 28,491 10,395 34.1%
BACLOFEN BACLOFEN 80 2,958 8,773 11.5%
ACETAMINOPHEN\OXYCODONE - 77 31,342 7,703 31.5%
TOFACITINIB XELJANZ XR 72 7,847 21,976 5.0%

View all 493 drugs →

Most Reported Drugs for Pain in extremity

#1 most reported
#2 most reported
#3 most reported