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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Persistent depressive disorder: Which Medications Are Safest? (69 Drugs Compared)

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69 medications are used for Persistent depressive disorder, with 392 combined adverse event reports. The most reported drugs for Persistent depressive disorder are SERTRALINE and RISPERIDONE.

392
Total Reports
69
Drugs Used

All Medications for Persistent depressive disorder Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
SERTRALINE Sertraline Hydrochloride 53 6,889 19,327 11.5%
RISPERIDONE Risperidone 38 4,120 18,771 5.2%
QUETIAPINE Quetiapine 35 13,610 31,386 18.6%
FLUOXETINE Fluoxetine 28 5,534 11,247 17.7%
ARIPIPRAZOLE Aripiprazole 26 3,863 20,713 5.8%
PAROXETINE Paroxetine 25 2,854 8,171 13.3%
ESCITALOPRAM OXALATE Escitalopram 24 3,531 11,942 11.6%
DULOXETINE Duloxetine Hydrochloride 22 4,044 10,622 7.7%
BUPROPION Bupropion Hydrochloride (XL) 19 8,577 10,246 24.1%
ALPRAZOLAM Alprazolam 18 16,072 15,996 33.2%
VENLAFAXINE Venlafaxine Hydrochloride 17 7,521 15,749 15.7%
VORTIOXETINE HYDROBROMIDE Trintellix 16 400 1,741 2.9%
LAMOTRIGINE Lamotrigine ER 15 6,604 17,639 13.7%
MIRTAZAPINE Mirtazapine 15 5,410 11,495 18.9%
DESVENLAFAXINE Desvenlafaxine Succinate 12 447 1,093 5.0%
BREXPIPRAZOLE Rexulti 9 673 1,269 5.1%
TRAZODONE Trazodone Hydrochloride 7 6,213 7,153 32.4%
ZOLPIDEM Zolpidem Tartrate 7 3,908 7,033 18.2%
PEROSPIRONE - 6 18 55 14.0%
BROTIZOLAM - 5 95 386 14.1%

View all 69 drugs →

Most Reported Drugs for Persistent depressive disorder

#1 most reported
#2 most reported
#3 most reported