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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Premenstrual syndrome: Which Medications Are Safest? (74 Drugs Compared)

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74 medications are used for Premenstrual syndrome, with 723 combined adverse event reports. The most reported drugs for Premenstrual syndrome are DROSPIRENONE\ETHINYL ESTRADIOL and YAZ.

723
Total Reports
74
Drugs Used

All Medications for Premenstrual syndrome Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
DROSPIRENONE\ETHINYL ESTRADIOL - 267 212 2,702 3.3%
YAZ - 81 18 868 0.9%
YASMIN - 64 18 763 1.0%
SERTRALINE Sertraline Hydrochloride 51 6,889 19,327 11.5%
FLUOXETINE Fluoxetine 41 5,534 11,247 17.7%
LEVONORGESTREL Mirena 31 142 6,322 0.1%
ETHINYL ESTRADIOL\ETONOGESTREL - 23 130 3,386 1.1%
OCELLA - 23 6 276 0.7%
BUPROPION Bupropion Hydrochloride (XL) 20 8,577 10,246 24.1%
ESCITALOPRAM OXALATE Escitalopram 17 3,531 11,942 11.6%
ETHINYL ESTRADIOL\NORETHINDRONE - 15 85 418 1.9%
DROSPIRENONE Angeliq 10 9 146 0.3%
DROSPIRENONE\ETHINYL ESTRADIOL\LEVOMEFOLATE - 8 5 138 1.3%
ETHINYL ESTRADIOL\LEVONORGESTREL - 8 104 1,046 2.3%
ETHINYL ESTRADIOL\NORELGESTROMIN - 8 12 78 0.2%
ETHINYL ESTRADIOL\NORGESTIMATE - 8 17 268 0.3%
LEUPROLIDE Fensolvi 8 11,858 10,499 16.7%
NAPROXEN Naproxen Sodium 8 5,127 12,849 9.7%
IBUPROFEN equate ibuprofen 7 6,705 29,386 7.7%
INSULIN ASPART NovoLog Mix 70/30 7 1,350 7,879 6.1%

View all 74 drugs →

Most Reported Drugs for Premenstrual syndrome

#2 most reported
#3 most reported