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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Pruritus: Which Medications Are Safest? (526 Drugs Compared)

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526 medications are used for Pruritus, with 8,782 combined adverse event reports. The most reported drugs for Pruritus are DUPILUMAB and CETIRIZINE.

8,782
Total Reports
526
Drugs Used

All Medications for Pruritus Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
DUPILUMAB Dupixent 1,629 1,536 17,008 0.4%
CETIRIZINE Cetirizine 1,196 4,787 8,423 10.0%
DIPHENHYDRAMINE Allergy Relief 515 10,508 6,849 40.7%
FEXOFENADINE Fexofenadine HCl 415 80 535 0.4%
HYDROXYZINE Hydroxyzine Hydrochloride 386 3,894 4,772 32.5%
KETOCONAZOLE Ketoconazole 346 132 330 2.4%
LORATADINE Curist Allergy Relief 345 372 1,472 1.5%
LEVOCETIRIZINE allergy relief 205 554 884 5.1%
DIFELIKEFALIN Korsuva 191 49 110 13.5%
HYDROCORTISONE Hydrocortisone Cream Intensive Healing 183 5,314 10,582 21.6%
CLOBETASOL CLOBETASOL PROPIONATE 175 107 610 1.4%
PREDNISONE prednisone 166 22,555 57,772 14.2%
NAPROXEN Naproxen Sodium 155 5,127 12,849 9.7%
TRIAMCINOLONE ACETONIDE Triamcinolone Acetonide 143 1,874 3,276 11.2%
GABAPENTIN Gabapentin 140 11,101 16,499 14.9%
ACETAMINOPHEN\CODEINE - 129 3,387 4,926 22.3%
CRISABOROLE Eucrisa 123 22 53 0.3%
DESLORATADINE Desloratadine 122 160 1,389 5.1%
OMALIZUMAB Omalizumab-igec 116 1,713 11,178 2.7%
ACETAMINOPHEN Hydrocodone Bitartrate and Acetaminophen 92 30,085 50,046 22.0%

View all 526 drugs →

Most Reported Drugs for Pruritus

#1 most reported
#2 most reported
#3 most reported