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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Sedation: Which Medications Are Safest? (261 Drugs Compared)

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261 medications are used for Sedation, with 5,258 combined adverse event reports. The most reported drugs for Sedation are PROPOFOL and MIDAZOLAM.

5,258
Total Reports
261
Drugs Used

All Medications for Sedation Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
PROPOFOL Propofol 1,714 1,970 6,577 12.3%
MIDAZOLAM Midazolam 1,360 1,808 4,691 16.2%
DEXMEDETOMIDINE Dexmedetomidine Hydrochloride in 0.9% Sodium Chloride 859 235 1,258 7.2%
FENTANYL FENTANYL 706 42,491 15,153 45.0%
SUFENTANIL Sufentanil Citrate 413 382 1,651 8.8%
KETAMINE KETAMINE HYDROCHLORIDE 283 1,009 3,362 12.6%
MIDAZOLAM\MIDAZOLAM - 197 236 350 20.4%
DIAZEPAM Diazepam 194 12,045 13,635 31.6%
LORAZEPAM Lorazepam 193 6,187 15,431 18.5%
REMIFENTANIL Remifentanil Hydrochloride 176 210 995 7.7%
MORPHINE Morphine Sulfate 131 38,212 17,386 31.7%
CISATRACURIUM cisatracurium besylate 123 224 610 13.0%
SEVOFLURANE Sojourn 108 272 1,413 6.3%
CLONAZEPAM Clonazepam 90 8,488 12,506 21.5%
QUETIAPINE Quetiapine 73 13,610 31,386 18.6%
HALOPERIDOL Haloperidol 71 1,882 7,393 11.8%
NOREPINEPHRINE NOREPINEPHRINE BITARTRATE 64 1,673 2,668 32.8%
FENTANYL\FENTANYL - 53 1,564 1,000 41.9%
LIDOCAINE Burn Relief 51 1,738 5,570 7.6%
CLONIDINE Clonidine hydrochloride 47 2,401 3,920 19.1%

View all 261 drugs →

Most Reported Drugs for Sedation

#1 most reported
#2 most reported
#3 most reported