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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Sedative therapy: Which Medications Are Safest? (154 Drugs Compared)

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154 medications are used for Sedative therapy, with 2,805 combined adverse event reports. The most reported drugs for Sedative therapy are PROPOFOL and MIDAZOLAM.

2,805
Total Reports
154
Drugs Used

All Medications for Sedative therapy Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
PROPOFOL Propofol 904 1,970 6,577 12.3%
MIDAZOLAM Midazolam 630 1,808 4,691 16.2%
DEXMEDETOMIDINE Dexmedetomidine Hydrochloride in 0.9% Sodium Chloride 604 235 1,258 7.2%
FENTANYL FENTANYL 376 42,491 15,153 45.0%
KETAMINE KETAMINE HYDROCHLORIDE 197 1,009 3,362 12.6%
DIAZEPAM Diazepam 101 12,045 13,635 31.6%
MIDAZOLAM\MIDAZOLAM - 91 236 350 20.4%
MORPHINE Morphine Sulfate 89 38,212 17,386 31.7%
LORAZEPAM Lorazepam 87 6,187 15,431 18.5%
SUFENTANIL Sufentanil Citrate 74 382 1,651 8.8%
FENTANYL\FENTANYL - 52 1,564 1,000 41.9%
CISATRACURIUM cisatracurium besylate 47 224 610 13.0%
HALOPERIDOL Haloperidol 41 1,882 7,393 11.8%
QUETIAPINE Quetiapine 39 13,610 31,386 18.6%
HYDROMORPHONE Hydromorphone Hydrochloride 37 28,491 10,395 34.1%
REMIFENTANIL Remifentanil Hydrochloride 36 210 995 7.7%
SEVOFLURANE Sojourn 36 272 1,413 6.3%
OLANZAPINE Olanzapine 30 5,535 21,934 10.8%
ETOMIDATE ETOMIDATE injection, solution 23 80 240 10.9%
ZOLPIDEM Zolpidem Tartrate 22 3,908 7,033 18.2%

View all 154 drugs →

Most Reported Drugs for Sedative therapy

#1 most reported
#2 most reported
#3 most reported