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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Sleep disorder: Which Medications Are Safest? (480 Drugs Compared)

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480 medications are used for Sleep disorder, with 13,355 combined adverse event reports. The most reported drugs for Sleep disorder are QUETIAPINE and ZOLPIDEM.

13,355
Total Reports
480
Drugs Used

All Medications for Sleep disorder Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
QUETIAPINE Quetiapine 1,362 13,610 31,386 18.6%
ZOLPIDEM Zolpidem Tartrate 1,352 3,908 7,033 18.2%
SODIUM OXYBATE sodium oxybate 1,311 537 6,147 0.9%
TRAZODONE Trazodone Hydrochloride 750 6,213 7,153 32.4%
MIRTAZAPINE Mirtazapine 699 5,410 11,495 18.9%
ZOPICLONE - 652 2,624 7,438 18.5%
DIPHENHYDRAMINE\IBUPROFEN - 589 111 118 2.8%
CLONAZEPAM Clonazepam 580 8,488 12,506 21.5%
ALPRAZOLAM Alprazolam 505 16,072 15,996 33.2%
RISPERIDONE Risperidone 449 4,120 18,771 5.2%
LORAZEPAM Lorazepam 358 6,187 15,431 18.5%
SUVOREXANT BELSOMRA 343 219 572 2.3%
MELATONIN Melatonin 1527 342 812 2,253 19.8%
OLANZAPINE Olanzapine 263 5,535 21,934 10.8%
ZOLPIDEM\ZOLPIDEM - 262 1,996 2,369 33.9%
AMITRIPTYLINE AMITRIPTYLINE HYDROCHLORIDE 232 4,837 7,290 23.7%
TEMAZEPAM Temazepam 215 2,592 1,162 45.0%
DIAZEPAM Diazepam 170 12,045 13,635 31.6%
DIPHENHYDRAMINE Allergy Relief 153 10,508 6,849 40.7%
ESZOPICLONE Eszopiclone 151 447 448 18.3%

View all 480 drugs →

Most Reported Drugs for Sleep disorder

#1 most reported
#2 most reported
#3 most reported