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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Somnolence: Which Medications Are Safest? (147 Drugs Compared)

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147 medications are used for Somnolence, with 10,872 combined adverse event reports. The most reported drugs for Somnolence are SODIUM OXYBATE and CALCIUM OXYBATE\MAGNESIUM OXYBATE\POTASSIUM OXYBATE\SODIUM OXYBATE.

10,872
Total Reports
147
Drugs Used

All Medications for Somnolence Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
SODIUM OXYBATE sodium oxybate 6,551 537 6,147 0.9%
CALCIUM OXYBATE\MAGNESIUM OXYBATE\POTASSIUM OXYBATE\SODIUM OXYBATE - 3,257 68 1,357 0.9%
SOLRIAMFETOL SUNOSI 240 9 75 0.4%
MODAFINIL Modafinil 177 157 556 4.7%
ARMODAFINIL Armodafinil 143 27 240 1.1%
AMPHETAMINE ASPARTATE\AMPHETAMINE\DEXTROAMPHETAMINE SACCHARATE\DEXTROAMPHETAMINE - 73 688 767 4.3%
METHYLPHENIDATE Methylphenidate Hydrochloride 69 1,163 4,620 3.8%
IPRATROPIUM Ipratropium bromide 50 860 3,389 11.4%
PITOLISANT Wakix 46 7 70 0.8%
DIPHENHYDRAMINE\IBUPROFEN - 36 111 118 2.8%
ZOLPIDEM Zolpidem Tartrate 35 3,908 7,033 18.2%
XYREM - 29 20 159 4.3%
MIRTAZAPINE Mirtazapine 26 5,410 11,495 18.9%
QUETIAPINE Quetiapine 22 13,610 31,386 18.6%
CLONAZEPAM Clonazepam 20 8,488 12,506 21.5%
NUVIGIL - 20 1 13 0.4%
MELATONIN Melatonin 1527 17 812 2,253 19.8%
ARIPIPRAZOLE Aripiprazole 14 3,863 20,713 5.8%
TRAZODONE Trazodone Hydrochloride 14 6,213 7,153 32.4%
LISDEXAMFETAMINE DIMESYLATE LISDEXAMFETAMINE DIMESYLATE 13 122 2,028 0.7%

View all 147 drugs →

Most Reported Drugs for Somnolence

#1 most reported
#3 most reported