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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Substance abuse: Which Medications Are Safest? (126 Drugs Compared)

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126 medications are used for Substance abuse, with 476 combined adverse event reports. The most reported drugs for Substance abuse are ARIPIPRAZOLE and NALTREXONE.

476
Total Reports
126
Drugs Used

All Medications for Substance abuse Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
ARIPIPRAZOLE Aripiprazole 58 3,863 20,713 5.8%
NALTREXONE NALTREXONE HYDROCHLORIDE 54 1,106 2,843 4.3%
BUPRENORPHINE\NALOXONE - 36 1,119 2,872 5.2%
METHADONE METHADONE HYDROCHLORIDE 33 10,719 5,514 40.8%
FENTANYL FENTANYL 20 42,491 15,153 45.0%
COCAINE NUMBRINO 19 8,171 3,863 57.5%
QUETIAPINE Quetiapine 18 13,610 31,386 18.6%
ALCOHOL Advanced Hand Sanitizer 17 15,215 6,310 69.8%
BUPRENORPHINE Buprenorphine and Naloxone 17 25,813 9,467 31.5%
NITROUS Nitrous Oxide 17 129 440 12.3%
DIAMORPHINE - 15 4,735 1,656 52.6%
GABAPENTIN Gabapentin 14 11,101 16,499 14.9%
PREGABALIN Pregabalin 14 8,959 22,920 8.8%
AMBRISENTAN AMBRISENTAN 13 10,291 32,910 11.9%
AMPHETAMINE AMPHETAMINE SULFATE 12 3,355 1,300 55.8%
LEVOTHYROXINE LEVOTHYROXINE SODIUM 12 4,539 12,155 7.4%
CLONAZEPAM Clonazepam 11 8,488 12,506 21.5%
MORPHINE Morphine Sulfate 11 38,212 17,386 31.7%
RISPERIDONE Risperidone 11 4,120 18,771 5.2%
CANNABIS SATIVA SUBSP. INDICA TOP - 10 3,040 2,907 35.2%

View all 126 drugs →

Most Reported Drugs for Substance abuse

#1 most reported
#2 most reported
#3 most reported