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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Trisomy 21: Which Medications Are Safest? (87 Drugs Compared)

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87 medications are used for Trisomy 21, with 285 combined adverse event reports. The most reported drugs for Trisomy 21 are PALIVIZUMAB and AZACITIDINE.

285
Total Reports
87
Drugs Used

All Medications for Trisomy 21 Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
PALIVIZUMAB Synagis 97 1,248 6,461 10.9%
AZACITIDINE Azacitidine 16 6,641 9,028 34.4%
AMBRISENTAN AMBRISENTAN 14 10,291 32,910 11.9%
CYTARABINE cytarabine 12 9,089 17,861 20.5%
LEVETIRACETAM Levetiracetam 12 4,322 19,165 6.9%
METHOTREXATE Methotrexate 12 21,265 68,793 8.4%
RISPERIDONE Risperidone 12 4,120 18,771 5.2%
VALPROATE Valproate Sodium 12 1,000 6,625 6.3%
SOMATROPIN Nutropin AQ NuSpin 10 11 1,350 4,957 2.0%
OLANZAPINE Olanzapine 10 5,535 21,934 10.8%
DEXAMETHASONE Dexamethasone Sodium Phosphate 9 22,319 51,311 17.8%
DEXTROMETHORPHAN HYDROBROMIDE\QUINIDINE - 8 2,936 282 55.3%
VIGABATRIN Vigabatrin 8 1,091 3,607 9.0%
ARIPIPRAZOLE Aripiprazole 7 3,863 20,713 5.8%
CARBAMAZEPINE Carbamazepine 7 2,156 9,608 8.8%
CORTICOTROPIN OHM Pituitarum Complex 7 496 2,369 4.2%
HUMAN IMMUNOGLOBULIN G BIVIGAM 7 5,286 16,081 7.5%
ZONISAMIDE Zonisamide 7 299 1,424 6.3%
TOPIRAMATE Topiramate 6 3,527 7,098 12.3%
VINCRISTINE VinCRIStine Sulfate 6 14,548 26,911 20.1%

View all 87 drugs →

Most Reported Drugs for Trisomy 21

#1 most reported
#2 most reported
#3 most reported