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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Type 2 diabetes mellitus: Which Medications Are Safest? (674 Drugs Compared)

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674 medications are used for Type 2 diabetes mellitus, with 241,710 combined adverse event reports. The most reported drugs for Type 2 diabetes mellitus are INSULIN GLARGINE and METFORMIN.

241,710
Total Reports
674
Drugs Used

All Medications for Type 2 diabetes mellitus Ranked by Safety Reports

Drug Brand Reports Deaths (all) Hosp. (all) Death Rate
INSULIN GLARGINE Lantus Solostar 41,731 2,311 13,970 2.3%
METFORMIN Metformin Hydrochloride 25,080 11,550 40,702 12.7%
DULAGLUTIDE Trulicity 24,742 1,054 6,536 1.4%
SEMAGLUTIDE WEGOVY 17,910 792 11,258 1.3%
INSULIN LISPRO Humalog KwikPen 16,871 1,285 10,547 1.6%
EXENATIDE Exenatide 16,403 1,228 2,512 3.9%
TIRZEPATIDE Zepbound 14,571 455 5,527 0.5%
EMPAGLIFLOZIN Jardiance 12,176 1,624 12,216 4.4%
CANAGLIFLOZIN INVOKANA 10,795 544 9,503 2.2%
PIOGLITAZONE PIOGLITAZONE 8,418 1,954 1,485 16.6%
LIRAGLUTIDE Victoza 7,740 994 4,819 4.3%
INSULIN HUMAN Humulin N 6,567 831 5,963 3.0%
SITAGLIPTIN JANUVIA 6,353 2,412 6,668 12.1%
INSULIN ASPART NovoLog Mix 70/30 5,748 1,350 7,879 6.1%
DAPAGLIFLOZIN QTERN 5,444 3,633 8,467 17.0%
ALBIGLUTIDE - 4,705 33 323 0.4%
INSULIN DEGLUDEC TRESIBA 4,068 555 2,549 4.8%
DEVICE - 3,625 398 1,716 3.1%
INSULIN DETEMIR Levemir 3,260 373 2,723 3.9%
DAPAGLIFLOZIN PROPANEDIOL FARXIGA 3,053 3,694 2,425 21.9%

View all 674 drugs →

Most Reported Drugs for Type 2 diabetes mellitus

#1 most reported
#2 most reported
#3 most reported